Neuromyelitis optica spectrum disorder associated with herpes zoster:a case report / 中华神经科杂志

We report here a case of myelitis of the cervical spinal cord in a 59-year-old woman presented with right arm weakness and numbness. Cervical myelitis developed three weeks after the eruption of zoster rash from the C2 to C5 dermatomes. The serum aquaporin-4 antibody was detected using the cell based transfection immunofluorescence assay. MRI of the cervical spine revealed abnormal cord signal. Cerebrospinal fluid analysis demonstrated varicella-zoster virus DNA was not detected. The patient was diagnosed with neuromyelitis optica spectrum disorder, supporting the hypothesis that the pathogenesis of neuromyelitis optica spectrum disorders is triggered by infection.

Moyamoya syndrome as an unusual presenting manifestation of systemic lupus erythematosus in a young woman

To describe a rare case of moyamoya syndrome associated with systemic lupus erythematosus [SLE]. A 22-year-old woman presented with left-sided hemiparesis in addition to fever, fatigue and malar rash. Brain magnetic resonance imaging revealed acute infarction in the right middle cerebral artery territory. Cerebral angiography showed features of moyamoya syndrome. Brain biopsy showed evidence of vasculitis. She responded well to steroid therapy. This case represented a rare co-occurrence of SLE-related vasculitis and moyamoya syndrome. Early vascular imaging is critical in patients with SLE and suspected ischemic stroke