RESUMO
Objective:To investigate the value of the 8-channel eye surface phased array coil in improving image quality and demonstrating ocular masses on 3.0 T MR scanner.Methods:From July 2018 to January 2020, the data of orbital MRI in 692 patients with ocular masses on 6 medical centers were prospectively collected. The patients were simple randomly assigned into 8-channel eye surface phased array coil group (413 patients) or 8-channel head phased array coil group (279 patients), with the same MRI sequences. The signal to noise ratio (SNR) and contrast to noise ratio (CNR) were calculated in orbital anatomy structures and masses (eyelid mass, intraocular mass, lacrimal mass and orbital mass). The image quality scores including motion artifact, mass margin, the relationship between the mass and adjacent structures, and overall image quality were recorded. The differences of image quality between the two groups were compared by two independent sample t-test or Wilcoxon rank test. Results:The SNR and CNR were higher in eye surface coil group than those in head coil group ( P<0.05). The scores of ocular movement artifacts were higher in head coil group than those in surface coil group ( P<0.05). The scores of intraocular mass margin, the relationship between the mass and adjacent structures, and overall image quality were higher in surface coil group than those in head coil group ( P<0.001). There were no significant differences in mass margin, the relationship between the mass and adjacent structures, and overall image quality scores of eyelid, lacrimal gland, and orbital mass between the two groups ( P>0.05). Conclusion:3.0 T MR scanner combined with the 8-channel eye surface phased array coil can improve the SNR and CNR of orbital MR images, the demonstration of the intraocular mass margin and the relationship between the mass and adjacent structures.
RESUMO
Objective:To investigate the value of periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) in improving ability of demonstrating ocular masses on 3.0 T MR scanner.Methods:This study was a multi-center prospective study involving 6 centers. From July 2018 to January 2020, totally 413 patients with ocular masses from 6 centers were prospectively enrolled, and all of them underwent T 1WI and T 2WI, PROPELLER T 1 FLAIR and T 2WI, and contrast-enhanced scans. The signal intensity of eyelid, vitreous body, lacrimal gland, intraorbital segment of optic nerve, and orbital masses of eyelid, intraocular, lacrimal gland and retrobulbar were measured by two radiologists, and the signal to noise ratio (SNR) and contrast noise ratio (CNR) were calculated. The 5-point scoring method was used to evaluate the motion artefacts, tumor edges and the relationship between the tumor and adjacent structures, and the overall score of image quality was calculated. Paired t-test or Wilcoxon signed rank test was used to compare the image quality between PROPELLER and non-PROPELLER images. Results:The SNR and CNR of PROPELLER T 2WI were higher than those of non-PROPELLER T 2WI (all P<0.001). The SNR and CNR of PROPELLER T 1 FLAIR were lower than those of non-PROPELLER T 1WI (all P<0.05). The scores of artefacts and overall image quality in PROPELLER images were higher than those in non-PROPELLER images (all P<0.001). The tumor edge and the relationship between the tumor and adjacent structures scores of eyelid, intraocular, and lacrimal gland masses in PROPELLER images were higher than those in non-PROPELLER images (all P<0.001),while compared to non-PROPELLER images, retro-global masses in PROPELLER images showed no significant differences (all P>0.05). Conclusion:PROPELLER can reduce ocular motion artefacts, effectively improve image quality and ability of demonstrating anterior (eyelid, intraocular, and lacrimal gland) masses.
RESUMO
investigate the CT and MRI features of adult rhabdomyosarcoma (RMS) of extremities. Methods A retrospective analysis was carried out on CT and MRI findings of 10 patients with rhabdomyosarcoma of extremities confirmed by surgery and pathology in Wenzhou People′s Hospital and the Second Affiliated Hospital of Wenzhou Medical University. The site, size, shape, margin, density or signal, adjacent tissue changes and enhanced degree of the mass were observed. Results In the 10 cases, the mass was located in the thigh in 6 cases, in the calf in 3 cases, and in the upper arm in 1 case. The maximum diameter of the tumor was 2.9-22.5 (12.0 ± 7.2) cm. The masses were oval in 2 cases and irregular in 8 cases. The margins of the masses were clear in 2 cases and unclear in 8 cases. There was invasive destruction of adjacent bone in 3 cases, intratumoral necrotic cystic changes in 8 cases, intratumoral hemorrhage in 2 case, and lymph node metastasis in 3 cases. Four patients underwent plain CT scan: CT presented isodensity in 1 case and slightly lower density in 3 cases. The mass density was uniform in 1 case and uneven in 3 cases. CT value of the solid part of the mass was 27-47 (42 ± 6) HU in average. Three patients underwent enhanced CT scan: all the enhanced masses showed uneven enhancement, including 1 case of mild enhancement and 2 cases of moderate enhancement, with no enhancement of necrotic cystic lesion area and clear in lesion boundary. Nine patients underwent plain MRI scan: mass of 9 cases presented iso-signal or slightly lower signal on T1WI, including 4 cases with iso-signal and 5 cases with slightly lower signal. There were 7 cases of uneven signals and 2 cases of uniform signals. The mass presented high signal on T2WI, including 8 cases with uneven signals and 1 case with uniform signals, and the necrotic cystic lesion showed higher signal on T2WI. Seven patients underwent enhanced MRI scan: all the enhanced masses showed uneven enhancement, including significant enhancement in 5 cases, moderate enhancement in 2 cases, no enhancement in necrotic cystic lesion area, and "perivascular" phenomenon in 4 cases. Conclusions CT or MRI examination shows that the soft tissue tumor of the extremities presents low density on CT, equal or slightly low T1WI signal on MRI, and high signal on T2WI, with necrotic cystic lesion inside peripheral blood vessel density in the tumor, without calcification and significantly or moderately uneven enhancement should consider the possibility of RMS should be considered.
RESUMO
Objective@#To investigate the CT and MRI features of adult rhabdomyosarcoma (RMS) of extremities.@*Methods@#A retrospective analysis was carried out on CT and MRI findings of 10 patients with rhabdomyosarcoma of extremities confirmed by surgery and pathology in Wenzhou People′s Hospital and the Second Affiliated Hospital of Wenzhou Medical University. The site, size, shape, margin, density or signal, adjacent tissue changes and enhanced degree of the mass were observed.@*Results@#In the 10 cases, the mass was located in the thigh in 6 cases, in the calf in 3 cases, and in the upper arm in 1 case. The maximum diameter of the tumor was 2.9-22.5 (12.0 ± 7.2) cm. The masses were oval in 2 cases and irregular in 8 cases. The margins of the masses were clear in 2 cases and unclear in 8 cases. There was invasive destruction of adjacent bone in 3 cases, intratumoral necrotic cystic changes in 8 cases, intratumoral hemorrhage in 2 case, and lymph node metastasis in 3 cases. Four patients underwent plain CT scan: CT presented isodensity in 1 case and slightly lower density in 3 cases. The mass density was uniform in 1 case and uneven in 3 cases. CT value of the solid part of the mass was 27-47 (42 ± 6) HU in average. Three patients underwent enhanced CT scan: all the enhanced masses showed uneven enhancement, including 1 case of mild enhancement and 2 cases of moderate enhancement, with no enhancement of necrotic cystic lesion area and clear in lesion boundary. Nine patients underwent plain MRI scan: mass of 9 cases presented iso-signal or slightly lower signal on T1WI, including 4 cases with iso-signal and 5 cases with slightly lower signal. There were 7 cases of uneven signals and 2 cases of uniform signals. The mass presented high signal on T2WI, including 8 cases with uneven signals and 1 case with uniform signals, and the necrotic cystic lesion showed higher signal on T2WI. Seven patients underwent enhanced MRI scan: all the enhanced masses showed uneven enhancement, including significant enhancement in 5 cases, moderate enhancement in 2 cases, no enhancement in necrotic cystic lesion area, and "perivascular" phenomenon in 4 cases.@*Conclusions@#CT or MRI examination shows that the soft tissue tumor of the extremities presents low density on CT, equal or slightly low T1WI signal on MRI, and high signal on T2WI, with necrotic cystic lesion inside peripheral blood vessel density in the tumor, without calcification and significantly or moderately uneven enhancement should consider the possibility of RMS should be considered.
RESUMO
Objective To observe the efficacy of naloxone combined with Buyanghuanwu decoction on cong -nitive function of multi -infarct dementia(MID) patients.Methods 46 patients with MID were treated with Nalox-one Hydrochloride and Buyanghuanwu decoction .Mini -mental state examination ( MMSE ) , activity of daily living ( ADL) scale and hachinski ischemic scale score ( HIS) were used to estimate the therapeutic effect after the treatment for 30 days.Results Compared to 30 days before,the MMSE score and ADL score improved after the treatment (t=3.247,3.469,all P<0.05),and the score of HIS declined (t=3.384,P<0.05).Conclusion Application of nal-oxone combined with Buyanghuanwu decoction can significantly improve congnitive level and ADL function in multi -infarct dementia patients .