Comparative analysis for mental patients' life quality between developed and developing regions / 中南大学学报(医学版)

To explore the differences, causes and countermeasures for mental patients' life quality between developed and developing regions.
 Methods: Based on the Quality of Life Questionnaire for Psychiatric Patients (QOL-P) and adopting convenient random sampling method, a total of 340 mental patients in Shanghai and Guangxi were investigated, and the data were analyzed by methods of Paired Design Crosstabulation Data hypothesis test, multivariate logistic regression, and independent sample Kruskal-Wallis test. The differences in patients' life quality in the 2 regions and the influential factors were evaluated.
 Results: There were high consistency and correlation in the total scores of self-evaluation items G (self overall evaluation of life quality by patient) between the 2 regions. Region and gender significantly affected mental patients' life quality in the basic demography characteristics in the 2 regions. The differences between total scores of 4 independent samples grouped by region and sex were significant (P<0.01). The male and femal patients in Guangxi in the dimensions of physiology, psychology, society and symptom were better than those in Shanghai (P<0.01). There was certain homoplasy between the patients from Shanghai and those from Guangxi in terms of the most prominent matters that affect the mental patients' life quality, with the former being affected more seriously than the latter.
 Conclusion: To a certain extent, the mental patients' life quality in the developing region (Guangxi) is better than that in the developed region (Shanghai).

The Effect of Kakkonein on the Expression of NF-?B after Hepatic Ischemia Reperfusion Injury / 医学研究杂志

Objective To investigate the effect of kakkonein on the expression of NF-?B after hepatic ischemia reperfusion injury in rats.Methods Male Sprague-Dawley rats were randomly divided into three groups:pseudo-operation normal control group,hepatic ischemia reperfusion injury model group,kakkonein group.After hepatic ischemia and reperfusion,we analyzed the expression of NF-?B by the methods of Western blot and RT-PCR.Results After hepatic ischemia reperfusion,the NF-?B level increased obviously comparing with the normal group.Comparing to the hepatic ischemia reperfusion injury model group,the NF-?B level decreased after treated with kakkonein.Conclusion The apigenin has a prominent protective effect on hepatic ischemia reperfusion injury in rats through regulating the expression of NF-?B.