RESUMO
Objetivo: Describir las características clínico epidemiológicas de la Toxoplasmosis ocular activa, enpacientes del Servicio de Úvea del Instituto Nacional de Oftalmología (INO), desde el 2003 hasta el 2007. Materiales y Métodos: Estudio descriptivo retrospectivo, en el que se utilizaron 1498 historiasclínicas de pacientes del servicio de Úvea del Instituto Nacional de Oftalmología desde enero del 2003hasta octubre del 2007. Se obtuvieron 210 historias con diagnóstico de Toxoplasmosis ocular, siendo excluidos del estudio 109 pacientes por presentar: 16 IgG toxoplasma negativo, 46 sin coriorretinitis exudativa activa, 45 sin IgG toxoplasma y dos con opacidad vítrea intensa. La ceguera legal fue definida como la mejor agudeza visual corregida en el ojo afectado, menor o igual a 20/200. Se utilizaron comovariables: la edad, sexo, lugar de nacimiento y procedencia, características clínicas, tiempo de seguimiento, tiempo de inactivación de la lesión, complicaciones y agudeza visual final. Resultados: De 99 pacientes(102 ojos), el 55,56% fueron del sexo masculino. El grupo etario mayormente comprometido fueel de 21-30 años (31,31%). El 96,97% presentó lesión unilateral. La localización más frecuente fue la perifé-rica (61,90%). La complicación más frecuente: lesiones maculares (23,53%). El 7,07% de pacientes fue VIH(+), sin diferencias en la presentación clínica con respecto a los otros pacientes. Conclusiones: Lafrecuencia de Toxoplasmosis Ocular fue de 14,02%, inferior a los reportes mundiales (22,5%), lapresentación clínica-epidemiológica fue similar a la descrita en la literatura, mayormente en nacidos enel interior del país, en la tercera década de la vida, afección ocular unilateral y localización periférica de lalesión retinal. (AU)
Objective: To describe clinical - epidemiological characteristics of the ocular active toxoplasmosis, in patients of Uvea's Service of the National Institute of Ophthalmology, from 2003 to 2007. Materials and Methods: Retrospective descriptive study, which used 1498 patient records Uveal Service National Eye Institute from January 2003 to October 2007 as an information source. Were 210 patients obtained with diagnosis of ocular toxoplasmosis. Were 109 patients excluded: 16 IgG toxoplasma negative, 46 without exudative chorioretinitis activate, 45 without IgG toxoplasma, 02 with intense vitreous opacity. Legal blindness was definite to the best visual keenness corrected in the affected, minor eye or like 20/200. Variables were used as age, sex, place of birth and origin, clinical characteristics, time of follow-up, time of unactivation of the injury, complications and visual final keenness. Results: From 99 patients (102 eyes), 55.56 %. The age group mainly damaged was from 21 to 30 years old (31.31 %). 96.97 % showed unilateral injury. The most frequent location: peripheral (61.90 %).The most frequent complication: cataract (8.82 %). 7.07 % were HIV (+), without differences in the clinical presentation regarding the other patients. Conclusions: The predominance of the ocular Toxoplasmosis was 14.02 %, lower than the world reports (22.5 %).The clinical - epidemiologic presentation was similar to that described in the documentation, where the unilateral ocular condition and the peripheral location of the retinal injury affected to those born inside the country (Lima-Callao), in the third decade of the life. (AU)
Assuntos
Humanos , Masculino , Feminino , Toxoplasmose Ocular , Toxoplasmose Ocular/epidemiologia , Peru , Epidemiologia Descritiva , Estudos RetrospectivosRESUMO
The gastric pathogen Helicobacter pylori has been recognized as the major aetiologic agent of chronic gastritis and peptic ulcers and also a risk factor for gastric cancer; eradication of H pylori prevents peptic ulcer recurrence and may also decrease the prevalence of gastric cancer in high risk populations around the world. Currently the only accepted indication for treatment is ulcer disease and maltosa, infected with Helicobacter pilory. However treatment is difficult and easily develops resistance. The elaboration of an antibiotic profile is recommended after a treatment failure. There is a lack of information in developing countries so the aim of this work was to determine the antibiotic profile of 51 strains isolated from patients gastric biopsies attended at Hospital San Juan de Dios in Costa Rica, using egg yolk broth and finding a resistance of 63.0% to metronidazole with a breakpoint of 8.0 microg/ml and 20.0% resistance to tetracycline (MIC1.0 microg/ml), 6.0% to clarithromicyn with a MIC of 0.125 microg/ml. There was no resistance to amoxicilin (MIC 0.015 microg/ml). The microdilution technique is very laborious, but highly reproducible with results accordingly to previous work, and we recommended it for the designing of therapeutical scheme.