Clinical study on treatment of irritable bowel syndrome by massage combined with microecological regulators / 中国生化药物杂志

Objective To explore the treatment of irritable bowel syndrome, massage combined with microecological modulator therapy. Methods For 40 cases of irritable bowel syndrome patients using micro ecological regulator treatment, and classified as the control group, the other 40 patients used massage combined with microecological regulating agent treatment, and to the observation group, two groups of patients were in our hospital from March 2015 to January 2017. Results No significant difference between the two groups of patients in the treatment of the bacteria, after the number of packet treatmentintestinal aureus two groups had no significant difference, other bacteria were the observation group of patients obviously improved, improved the difference was significant(P<0.05). The total effective rate in observation group was 97.5%, only 75% of the control group, the observation group were significantly higher. Conclusion The clinical study of massage combined with microecological preparation in treatment of irritable bowel syndrome, the treatment is simple compared to micro ecological regulator, has certain advantages, can improve clinical symptoms of patients. At the same time, improve the therapeutic effect, so it is worthy of clinical use of priority.

Correlation between the C-reactive Protein gene polymorphism in periodontitis and the chronic periodontitis with type2 diabetes / 实用口腔医学杂志

Objective: To study the relationship between C-reactive protein (CRP) gene polymorphisms and the risk of chronic peri-odontitis and severe chronic periodontitis (CP) with type2 diabetes to confirm the effect of genetic factor in chronic periodontitis and chronic periodontitis with type2 diabetes. Methods; DNA was extracted by Chelex-100 from buccal swabs of patients who suffered from chronic periodontitis or chronic periodontitis with type2 diabetes and patients with healthy periodontium. PCR-RFLP was used to test the CRP genotype distribution. The correlationship between the incidence of chronic periodontitis and chronic periodontitis with type2 diabetes and CRP gene polymorphism was analyzed statistically. Results; There was no statistical difference in the distribution of CPR +1059 genotype and allele frequency between experiment group and control group (X~2 = 0. 223, P=0.994). The genotype and allele frequency distribution were in line with Hardy-Weinberg equilibrium. Conclusion; There is no correlation between CRP + 1059G/C single nucleotide polymorphisms and the susceptibility of chronic periodontitis as well as chronic periodontitis with type2 diabetes.