Clinical analysis of 10 cases with traumatic extra-articular ankylosis of temporomandibular joint / 实用口腔医学杂志

The data of 10 cases of traumatic extra-articular ankylosis of temporomandibular joint(TMJ),including the type of trauma and the type of ankylosis,pathology,treatment method,prognosis,and so on were collected and analyzed.A reference of diagnosis and treatment is provided.

Effects of bFGF on the proliferation of human salivary adenoid cystic carcinoma ACC-2 cell line and MEK/ERK, NF-?B signaling pathway / 实用口腔医学杂志

Objective:To investigate the effects of bFGF on the proliferation of human salivary adenoid cystic carcinoma cell ACC-2 in vitro. Methods:The effect of bFGF on proliferation of ACC-2 cell line was observed by MTT assay; ERK activity was measured by immuno-precipitation; and ERK and I-?B? expressions were assessed by Western blot. Results:bFGF can enhance the proliferation of ACC-2 cell line. Stimulated by bFGF, the proliferation ratio increased significantly. The intracellular ERK activity and p-ERK expression were increased and I-?B? expression was inhibited by different concentrations of bFGF. The above effects of bFGF can be attenuated by MEK inhibitor U0126. Conclusion:bFGF stimulates the proliferation of ACC-2 in the dose dependent manner, which may be due to up-regulating ERK, NF-?B signaling pathway.