RESUMO
Background. Blood transfusion is a life-saving procedure, which can occasionally be unsafe and result in a spectrum of adverse events. We aimed to determine the characteristics and type of acute transfusion reactions occurring in patients at a tertiary care centre. Methods. A retrospective study was conducted at the Department of Immunohaematology and Blood Transfusion, Dayanand Medical College and Hospital, Ludhiana, Punjab. All acute transfusion reactions reported to the department from 1 Jan 2012 to 31 March 2013 were evaluated. All the adverse reactions were recorded, analysed and classified on the basis of their clinical features and laboratory tests. Results. During the study period, 45 092 blood components were issued from the department and 190 transfusion reactions (0.42%) were reported. The most frequent were febrile non-haemolytic transfusion reactions (54.2%) followed by allergic reactions (36.3%), haemolytic reactions (1%) and non-specific reactions (8.5%). Conclusion. Each transfusion has to be monitored carefully with prompt recognition and treatment of acute transfusion reactions to decrease transfusion-related morbidity and mortality. Data from a well-functioning haemovigilance system can be used as a quality indicator for monitoring blood transfusion safety and contribute to evidence-based transfusion medicine.
RESUMO
Oro-facial granulomatosis includes a group of disorders which present as a chronic, non-ceasating granulomatous lesion involving the perioral tissues of face and oral mucosa. This condition was first referred by Mart in 1859, Hubschmann in 1894 and Luscher in 1949; later, Wiesenfeld in 1985 introduced the term “Oro-facial Granulomatosis” (OFG) which is characterized by persistent or recurrent soft tissue enlargement and oral ulceration. Hence, it is important to establish the diagnosis accurately because this condition sometimes is a manifestation of Crohn’s disease or Sarcoidosis. A case of Orofacial granulomatosis in a 15-year-old male is reported.