Autologous platelet-rich plasma eye drop versus artificial tear eye drop for symptomatic dry eye disease: A prospective comparative interventional study

Purpose: To evaluate and compare the efficacy of autologous platelet?rich plasma (aPRP) eye drop and artificial tear (AT) eye drop in moderate to severe symptomatic dry eye disease (DED). Methods: This prospective interventional study included 121 eyes of 61 patients of moderate to severe DED. Patients were divided into aPRP (31 patients) and AT (30 patients) group. Ocular Surface Disease Index (OSDI) score, tear film breakup time (TBUT) (s), corneal fluorescein staining (CFS) score, and Schirmer test score (mm) of both the groups were evaluated and compared pre?treatment and post?treatment at the end of 3 months. Results: The mean age of the aPRP group and AT group was 52.8 ± 12.8 years and 55.5 ± 13.4 years, respectively. At the end of 3 months, OSDI score reduced more in the aPRP group as compared to AT group, and the mean difference (?22.7) was statistically significant (P < 0.001). There was no significant difference in post?treatment Schirmer test score between the two groups (P = 0.44). Post?treatment improvement in TBUT and CFS score in the aPRP group was significantly higher in the aPRP group as compared to that in the AT group (P < 0.05). Bruising at the site of blood withdrawal was noted in two patients in the aPRP group. Conclusion: aPRP is safe and more effective than AT in treating patients with moderate to severe symptomatic DED

Effect of Pterygium Surgery on Keratometry Readings

Introduction: In many case Pterygium is found to causeastigmatism. Study aimed to find the effect of pterygiumexcision on keratomerty readings.Material and Methods: The present Retrospective study wasdone on 50 eyes of 50 patients, who had primary pterygiumand underwent pterygium surgery during period of October2016 to October 2017 in a tertiary care hospital. Informationthat was reviewed included preoperative uncorrected and bestcorrected visual acuity, auto refraction, auto keratometry anddetailed anterior segment and posterior segment examination.Results: Mean astigmatism changed from preoperative 5.94 ±3.82 Diopters (D) to 1.30 ± 1.07 D on 30th post operative dayshowing 4.64 ± 2.75 D of change in astigmatism.Conclusion: Pterygium can be a cause of low vision secondaryto corneal astigmatism. Pterygium excision reduces cornealastigmatism significantly, which improves vision.