RESUMO
Vitamin D level in serum is one such factor which has been found to be relevant in psoriasis so the aim of the present study is to assess the status of 25-hydroxy vitamin D in patients suffering from psoriasis along with the comparison of controls without psoriasis. Methods: The study included 40 cases and 40 controls. 40 outpatients, 30 male and 10 female, diagnosed clinically with psoriasis were enrolled in this study. Clinically diagnosed active psoriasis patients of any severity, aged more than 18 years, who had not been treated with phototherapy or vitamin D the previous 3 months, were enrolled as cases. Age, sex matched volunteers from the same geographical area attending the dermatology outpatient services as an attendee for the patient without any skin ailments were selected as controls. Appropriate informed consent in the local vernacular language was obtained from both cases and controls. Results: There was a statistically significant difference between cases and controls (P<0.0001). Vitamin D deficiency was observed in 78% of psoriasis patients compared with 28% of controls (P<0.001). Vitamin D deficiency was seen in 18 non-obese and 15 obese individuals. We did not find significant differences in vitamin D levels between patients with psoriasis and controls (P = 0.742). Conclusion: Vitamin D deficiency may be common in patients with psoriasis, and vitamin D has a role in immune regulation.