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1.
Artigo | IMSEAR | ID: sea-212190

RESUMO

Background: Ossification of the posterior longitudinal ligament (OPLL) is a complex multi-factorial disease process having both metabolic and biomechanical factors. The objective of this study was to assess the surgical out come and post operative functional improvement in patients with cervical OPLL at a tertiary care centre.Methods: This prospective observational study included 35 patients undergoing surgery for cervical OPLL in the department of neurosurgery, Care hospitals Hyderabad from October 2015 to October 2016 with follow up at 3months and 6 months.Results: Total 35 patients who underwent surgery, majority (77.15%) were males and (22.85%) were female. The age of the patients was between 30 to 70 years. The most common type of OPLL was found to be segmental and mixed type. Nurick grade improved by 1.12 in anterior approach vs 0.66 in posterior approach. Recovery rates observed in anterior approach is 57.72% while in posterior surgical approach it is 48.87%. No complication was observed in this study.Conclusions: OPLL is more common in males as compared to females. The average age of presentation is sixth decade. Younger patients have better outcomes. The most common variant of OPLL is segmental.  The recovery rate achieved from anterior approach are better than those from the posterior approach. Improvement in NURICKS score is more in anterior surgical group than in posterior surgical group. No complications seen in this study. No mortality seen in this study.

2.
Indian J Hum Genet ; 2009 Sept; 15(3): 140-142
Artigo em Inglês | IMSEAR | ID: sea-138887

RESUMO

Split-hand/split-foot malformation is a rare limb malformation with median clefts of the hands and feet and aplasia/hypoplasia of the phalanges, metacarpals and metatarsals. When present as an isolated anomaly, it is usually inherited as an autosomal dominant form. We report a case of autosomal recessive inheritance and discuss the antenatal diagnosis, genetic counseling and treatment for the malformation.


Assuntos
Criança , Deformidades Congênitas do Pé/diagnóstico , Deformidades Congênitas do Pé/epidemiologia , Deformidades Congênitas do Pé/genética , Deformidades Congênitas do Pé/terapia , Aconselhamento Genético , Deformidades Congênitas da Mão/diagnóstico , Deformidades Congênitas da Mão/epidemiologia , Deformidades Congênitas da Mão/genética , Deformidades Congênitas da Mão/terapia , Deformidades Congênitas dos Membros/diagnóstico , Deformidades Congênitas dos Membros/epidemiologia , Deformidades Congênitas dos Membros/genética , Deformidades Congênitas dos Membros/terapia , Humanos , Masculino , Diagnóstico Pré-Natal , Sindactilia/genética
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