Seroreactivity to Pf 155/RESA in Two Malaria Endemic Ecological Zones in Southern Ghana

Seroepidemiological data are becoming important tools in determining transmission patterns of malaria. We have undertaken a study in 2 different ecological zones in southern Ghana during both the dry and wet seasons. Virtually all the subjects studied were positive to the crude parasite antigen (92); with majority showing high titres in both areas. Whilst there was a statistical difference in Geometrical Mean Titre (GMT) between the two areas; seasonal variation was not seen. Antibody levels to the Pfl55/RESA and its repeat pepetide (EENV)6 increased progres notsively with age in endemic areas. These findings have relevance in determining malaria transmission in endemic areas

Nutritional status and levels of liver enzymes in Ghanaian alcoholics

The well nourished alcoholics appeared to have some protection from alcoholic liver damage; although their fat levels were higher which may predispose to cardiac disease. Alcoholics therefore; show some degree of impaired liver function which is more severe among those who are malnourished