Anterior Fibroblastic Proliferation of Lens Epithelial Cells in Acrylic Intraocular Lens

PURPOSE: To report upon two cases of anterior capsule opacification (ACO) proliferating into the pupillary region of the anterior surface of a single piece acrylic AcrySof(R) intraocular lens (IOL) (SA60AT, Alcon Laboratories, Inc., USA). The surgical removal of the ACO was also reported. METHODS: An 80-year-old woman and a 75-year-old woman underwent phacoemulsification with implantation of a single piece foldable AcrySof(R) IOL in the posterior capsular bag. ACO proliferating from the opposite sides of the IOL along the central axis were found three months after surgery. To recover visual acuity in the 80-year-old woman's eye, ACO was surgically removed with a Sinskey hook and irrigation and aspiration system. RESULTS: The patient's visual acuity was recovered after surgical removal of the ACO. Histopathologic findings of the removed tissues revealed fibroblastic proliferation of lens epithelial cells. The ACO in 75-year-old woman's eye was not treated, as it was not associated with a visual disturbance. CONCLUSIONS: In eyes containing an AcrySof(R) IOL, clinically significant ACO proliferation into the pupillary region along the central axis can occur. Surgical removal can be beneficial for recovery of visual acuity.

Tear Function and Ocular Surface Findings in Premature and Term Babies

PURPOSE: To describe the ocular surface and tear function findings in premature and term babies. METHODS: Sixty eyes of 30 premature babies and 60 eyes of 30 healthy term babies were studied. The subjects underwent routine ophthalmic examinations: corneal sensitivity test, corneal fluorescein test, Schirmer test with anesthesia, tear breakup time test, lipid layer pattern test and conjuctival impression cytology. RESULTS: The mean corneal sensitivity scores were 35.2+/-5.0 mm and 54.2+/-3.7 mm in the premature and term babies, respectively (P0.001). Mean squamous metaplasia scores were 1.05+/-0.59 in the premature and 0.18+/-0.39 in the term babies (P<0.001). CONCLUSIONS: Premature infants had decreased tactile corneal sensitivity and reduced basal tear secretion as compared with full term infants. The premature infants did not have severe ocular surface disease from dry eyes because the lipid layers provide a protective effect for the ocular surface.

Tear Function and Ocular Surface Findings in Premature and Term Babies

PURPOSE: To describe the ocular surface and tear function findings in premature and term babies. METHODS: Sixty eyes of 30 premature babies and 60 eyes of 30 healthy term babies were studied. The subjects underwent routine ophthalmic examinations: corneal sensitivity test, corneal fluorescein test, Schirmer test with anesthesia, tear breakup time test, lipid layer pattern test and conjuctival impression cytology. RESULTS: The mean corneal sensitivity scores were 35.2+/-5.0 mm and 54.2+/-3.7 mm in the premature and term babies, respectively (P0.001). Mean squamous metaplasia scores were 1.05+/-0.59 in the premature and 0.18+/-0.39 in the term babies (P<0.001). CONCLUSIONS: Premature infants had decreased tactile corneal sensitivity and reduced basal tear secretion as compared with full term infants. The premature infants did not have severe ocular surface disease from dry eyes because the lipid layers provide a protective effect for the ocular surface.