two-year study of survival rate in children with Wilms tumor treated at Besat hospital of Hamadan [2005-2009]

Wilms tumor is one of the most common renal tumors in children. This type of tumor - accounting for 6 percent of tumors in children - shows a good prognosis if treated in time. This study is to investigate the clinical and pathologic findings as well as response to treatment in Iranian children with Wilms tumor treated at Besat hospital of Hamadan [2005-2009]. In this descriptive cross-sectional study all the 24 children - with confirmed diagnosis of Wilms tumor [by biopsy] treated at hematology ward [Hamadan Besat Hospital] from 2005 to 2009 - were followed up by monthly examination and 3-monthly Para-clinical evaluations after treatment. Patients were at 3 stages of the disease phase at the time of diagnosis. Two patients had unfavorable histology. The most common clinical finding was abdominal mass. 2-year survival of the patients in stages 1 and 2, and stages 3 and 4 was 100% and 83%, respectively. Out of the total number of the patients, 4 cases referred with the recurrence of the tumor [16.7%]. Two of them were expired. The findings of the present study showed that the survival rate observed in this study was better than other studies in this field

Seizure as the first presentation of Glucose-6-Phosphate dehydragenase deficiency in a 3-year-old child

Seizure is a rare presentation for acute hemolysis due to G6PD deficiency. We report a previously healthy boy who presented initially with seizure and cyanosis and subsequently acute hemolysis, due to glucose-6-phosphate dehydrogenase defeciency [G6PD] and probably secondary methemoglobinemia, following the ingestion of fave beans

[Gallblader sonographic abnormality following ceftriaxone treatment in children]

Considering the relatively wide application of ceftriaxone in pediatric infectious diseases and its side effects, this study was done to determine gallblader sonographic abnormality following ceftriaxone treatment in children. This descriptive cross-sectional study was carried out on 60 patients age 1 month up to 12 years in Besat hospital, Hamadan, Iran during 2007. The sonographic abnormal finding of gallbladder before ceftriaxone therapy and 5 days after therapy were recorded. In case of any abnormality in gallblader sonography was repeated twice a week in the first two weeks and afterward once a week up to disappearance of abnormalities. Gallblader sonographic abnormality were observed in 10 cases [16.5%]. Out of them, 8 and 2 patients had bile stone and bile sludge, respectivley. The patients did not show any clinical manifestations. There was no relation between age and sex with abnormal findings. Gallblader abnormality completely were disappeared in the worst cases by sixteen days. This study showed that the incidence of either gallstone or biliary sludge after treatment with ceftriaxone was 16.5% which is relatively similar to other studies

Distribution by location of CT - diagnosed primary intracerebral hemorrhage in Isfahan

Intracerebral hemorrhage [ICH] is the third most frequent cause of stroke and accounts for 10 to 15 percent of all strokes in whites and 30 percent of them in blacks and Asian Population. The commoner sites of hemorrhages are different among populations and complications of them are different too. In the present descriptive observational study, we studies 226 ICH patients admitted in Al-Zahra Hospital in Isfahan, Iran, from November 2001 to November 2003 and evaluated them for their symptoms and signs according to size and location of their hemorrhages recognized by CT-scan at the time of admission. From our 226 patients [126 men and 100 women], 38.5% of them had thalamic hemorrhage, 24% had lobar hemorrhage, 22.5% had putaminal hemorrhage, 8% had pontine hemorrhage, 6% had cerebellar hemorrhage, and 1.3% had internal capsular hemorrhage. Seizure was commoner in lobar and putaminal hemorrhages. Vomiting was present in 100% of cerebellar hemorrhage cases. Headache was present in 100% of cerebellar hemorrhage cases and between 66-83% of cases with hemorrhage cases in other sites. Coma was common in pontine hoemorrhage. ICH accounts for 28.5% of our all stroke admissions.The incidence of intracerebral hemorrhage increases with age, reaching a maximum between the ages of 60 and 80 years old, and is higher in men than women and right side than the left side. We found that thalamic hemorrhage was the commonest site of hemorrhage among our patients second by lobar hemorrhage and more than half of our patients had headache or vomiting on the day of admission. Overall acute mortality rate depends mainly on the position and size of hemorrhage, which we can estimate them by the CT- scan. Diabetes mellitus is not considered as a risk factor, in contrast to hypertension