RESUMO
Background and Purpose: Thyroid autoimmune disease is the most common thyroid disorder in low-iodine intake areas; evaluation of thyroid peroxidase antibodies [TPOAb], anti- Thyoglubolin [TGAb] and anti-microsomal [TMAb] in most patients with hypothyroidism is of significant importance
Therefore, the present study was conducted to determine the role of anti-thyroid antibodies in patients with hypothyroidism in Sabzevar, Iran
Methods and Materials: This is a cross-sectional descriptive analytical study where 382 subjects with TSH above normal and T3 and T4 below normal were selected through non-probability convenient sampling. Their TSH, TPOAb, TGAb and TMSb were measured through Eliza method. The obtained data were analyzed in SPSS 15 using chi-square, independent t-test and Pearson correlation coefficient, where P< 0.05 was considered significant
Results: TPOAb, TGAb and TMSb in men and women with TSH higher than 10 mIU/ml were 72.3%, 78.3% and 50% positive respectively. In 72.3% of the subjects, TPOAb was above normal; in 78.5% of them TMAb was higher, and in 50% of them TGAb was higher. The highest rate of correlation was observed between TGAb and TPOAb [r=0.89]
Conclusion: The results indicated that, in the population studied, TPOAb, TMAb and TGAb were higher than the normal rates, and that TPOAb and TGAb are more remarkably changing to higher rates than TMAb
RESUMO
Background and Purpose: Vulvovaginal candidiasis is one of the most common infections in women and is caused by various types of candidiasis with different patterns of resistance against drugs. The present study was conducted to determine the various species of candidiasis in women admitted to Mobini Hospital in Sabzevar, Iran in order to make preventive recommendations for medical doctors
Methods and Materials: This cross-sectional descriptive analytical research was conducted on 231 women admitted to Mobini Hospital in Sabzevar, Iran, complaining of vaginal secretions. After getting the ethics committee permissions and obtaining the informed consent of the participants, at the same time as measuring vaginal pH, two swaps were used for collecting samples of secretions from lateral and posterior fornix. They were examined for yeasts and were then cultured in saburu dextrose. Grown yeasts were detected based on their macroscopic and microscopic features, tubulation in blood serum and biochemical characteristics using Yeast Plus System. The obtained data were analyzed in SPSS 11 using chi-square and bi-dimensional tables
Results: Positives results in direct examination results were 7.35%, and in culture the positive results were 26.8%. In detecting processes, candida albicans yeast [38.7%], Candida kefyr [17.7%], Saccharomyces cerevisiae [14,5%]; candia tropicalis [9.6%], Candida glabrata [8%], candida cruse [3.2%] were isolated with other non-pathogenic yeasts including Candida rugosa, Candida lipolytica, trycospron bejli, Blastoschizomyces capitatus [6.4%]
Conclusion: Non-pathogenic yeasts were isolated from patients with defective immunity systems, and need to be considered in patients with vaginal infections