RESUMO
Aims: To determine the presence of rabies virus neutralizing antibodies (rVNA) as well the potency of the rVNA in rabies occupational risk humans in Niger State of Nigeria. Study Design: Cross-sectional study. Place and Duration: Research was conducted at the Department of Veterinary Public Health, Ahmadu Bello University, Zaria, Nigeria and Rabies Unit, Centers for Disease Control and Prevention, CDC, Atlanta, USA, between May, 2012 and March, 2013 Materials and Methods: A total of 185 human volunteers were recruited from rabies risk occupational groups who filled a structured questionnaire on their previous bite history and vaccination status, between May and July, 2012. A 2 ml each of blood from volunteers was collected and centrifuged at 3000 rpm for 10 minutes and sera separated into pre-labeled vacutainers. Standard Rapid fluorescent focus inhibition test (RFFIT) was used to detect the presence of rVNA in the sera. Further end point titration of the rVNA positive human sera was conducted to determine the potency. Results: The results indicated that, detectable titre of rVNA was recorded in 16.4% (23 of 140) viable human sera screened. Although from the questionnaire survey, 21.7% (5 out of the 23 positives) responded to have been vaccinated over ten years prior. At least 3 of the respondents (1 dog butcher and 2 dog meat consumers) who responded not previously vaccinated had some neutralizing antibody titre range of 0.65 – 0.7 IU/ml which is above the minimum protective titre (0.5IU/ml) recommended by WHO. Similarly, 3 respondents (2 veterinarians and 1 animal health personnel) who responded to have been previously vaccinated (> 10 years earlier) yet had a high titre range of 0.5 – 5.4IU/ml. The highest specific rate for rVNA of 25% each was seen amongst the dog butchers and pet owners followed by hunters (20%) and dog meat consumers (14.8%). Up to 125 (67.6%) of the volunteers do consume dog meat with only 12 (9.6%) of them being dog butchers who source dogs for slaughter from households within and outside their territories. Conclusion: Although the WHO minimum protective titre of rVNA is 0.5 IU/ml, the presence of relatively high titres amongst these risk groups in this report is an indication of a serious public health threat. This study recommends the vaccination of rabies high risk groups and further screening of rabies occupational risk and non risk groups in the study area and Nigeria at large.
RESUMO
Elastofibroanas are rare benign soft tissue tumours that are almost always located at the inferior pole of the scapula, deep to the serrains anterior muscle, Their anatomical location, a distinctive clinical symptom and radiological particularities distinguish them from malignant soft tissue tumours. We report a case of a 48 years old man who had presented an under scapular mass. Clinical exam found a 70 mm mobile mass. CT scan showed a soft tissue neoplasm deep to the peri-scapular muscles. We processed to a total excision of this mass. Histological study showed an elastofibroma