Clinical significance of prostatic-specific antigen levels in patients with benign prostatic hyperplasia complicated by low urinary tract syndrome / 中华男科学杂志

<p><b>OBJECTIVE</b>To evaluate the clinical significance of prostatic-specific antigen (PSA) levels in patients with benign prostatic hyperplasia (BPH) complicated by low urinary tract syndrome( LUTS).</p><p><b>METHODS</b>The levels of tPSA, fPSA and fPSA/tPSA ratio were detected and compared in 520 cases of BPH with LUTS and 196 cases without LUTS.</p><p><b>RESULTS</b>The mean levels of tPSA in the cases of BPH with LUTS and without LUTS were (5.13 +/- 2.49) microg/L and (1.73 +/- 1.26) microg/L respectively (P<0.01). The mean levels fPSA were (1.57 +/- 0.80) microg/L and (0.54 +/- 0.38) microg/L respectively (P < 0.01). The mean ratios of fPSA/tPSA were (0.31 +/- 0.09) and (0.30 +/- 0.11) respectively ( P > 0.05).</p><p><b>CONCLUSION</b>The levels of tPSA, fPSA are significantly higher in the cases of BPH with LUTS than those in the cases without LUTS, but the ratio of fPSA/tPSA is stable in BPH.</p>

Modified cystectomy with preservation of erectile and ejaculatory functions in men with nonmalignant bladder disease / 中华男科学杂志

<p><b>OBJECTIVES</b>To evaluate modified cystectomy with preservation of erectile and ejaculatory functions in men with nonmalignant bladder disease.</p><p><b>METHODS</b>Seven cases with average age of 27 years presented with bladder disease necessitating cystectomy, including 2 cases of tuberculous contractile bladder, 1 case of extensive polypoid cystitis glandularis, 4 cases of late stage of neurogenic bladder. All patients wished to maintain erectile and ejaculatory functions after the operation. We performed a modified simple cystectomy with preservation of the vasa deferens, seminal vesicles, prostate and neurovascular bundles, as well as construction of an Indiana pouch or ileal neobladder.</p><p><b>RESULTS</b>Average operative time was 5 h 45 min without perioperative complications in this group. Follow-up ranged from 9 to 60 months. Erectile and ejaculatory functions were normal in all cases. All patients remained completely continent and no dysuria in neobladder, and there was no difficulty in inserting catheter to empty pouch. Upper urinary tract was in good condition 3 and 24 months after operation.</p><p><b>CONCLUSIONS</b>Modified cystectomy with preservation of the vasa deferens, seminal vesicles, prostate and neurovascular bundles is an effective and reliable option for the patients who wish to maintain their fertility and erectile function after surgery.</p>