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1.
China Journal of Orthopaedics and Traumatology ; (12): 531-535, 2015.
Artigo em Chinês | WPRIM | ID: wpr-240999

RESUMO

<p><b>OBJECTIVE</b>To compare clinical outcomes of superior labrum from anterior to posterior (SLAP) repair and biceps tenodesis in treating type I SLAP injury.</p><p><b>METHODS</b>From March 2009 to March 2012, 38 patients with type II SLAP injury were treated with SLAP repair and biceps tenodesis, and all patients were unilateral SLAP injury. Sixteen patients treated with biceps tenodesis included 8 males and 7 females with an average age of (49.3±3.7) years old (ranged, 45 to 54); 10 cases were on the left side and 6 cases on the right side; 10 cases were caused by falling down, 2 cases were caused by throwing damage and 4 cases were caused by daily life damage; the time from injury to operation were from 3 to 8 weeks. Twenty-two patients treated with SLAP repair included 14 males and 8 females with an average age of (49.0±2.8) years old (ranged, 44 to 56); 13 cases were on the left side and 9 cases were on the right side; 14 cases were caused by falling down, 5 cases were caused by throwing damage and 3 cases were caused by daily life damage; the time from injury to operation were from 3 to 7 weeks. Preoperative, postoperative at 6 months, 1 year and 2 years' UCLA and SST score were compared between two groups.</p><p><b>RESULTS</b>There was no significant differences in UCLA and SST score between two groups before operation. At 6 months after operation, UCLA and SST score in biceps tenodesis group was higher than SLAP group, and action,range of anteflexion, strength of anteflexion, degree of satisfaction in biceps tenodesis group was higher than SLAP group. There was no significant meaning in SST and UCLA score between two groups at 1 and 2 years after operation.</p><p><b>CONCLUSION</b>Short-term efficacy of biceps tenodesis for SLAP injury is better than SLAP repair, but long-term efficacy is fairly.</p>


Assuntos
Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos de Casos e Controles , Estudos Retrospectivos , Articulação do Ombro , Ferimentos e Lesões , Cirurgia Geral , Traumatismos dos Tendões , Cirurgia Geral , Tenodese
2.
Chinese Medical Journal ; (24): 257-261, 2012.
Artigo em Inglês | WPRIM | ID: wpr-333505

RESUMO

<p><b>BACKGROUND</b>The aim of this research was to determine the efficacy of combination therapy using an alginate dressing and mouse epidermal growth factor (mEGF) on proliferation and differentiation of epidermal stem cells (ESCs) in patients with refractory wounds.</p><p><b>METHODS</b>Eighteen patients (12 males and 6 females, aged from 18 to 61 years (mean 36.4 years)) with various skin wounds, were treated by dressing changing for one month. The wounds were located in the foot (11), calf (3), thigh (2) and forearm (2). The patients were randomly divided into 3 groups: alginate dressing and mEGF (group A; n = 6), mEGF (group B; n = 6) and control (group C; n = 6). Wound closure indexes were measured at 7, 14, 21 and 28 days. Samples were harvested for pathologic examination, at 7 and 14 days following treatment. Cytokeratin 10 (CK10) and cytokeratin 15 (CK15) positive cells were evaluated using the super-sensitivity (SP) immunohistochemical staining technique.</p><p><b>RESULTS</b>Wound healing was promoted in groups A and B. In group A, the wound closure index was increased significantly (P < 0.05), and in one case the maximum cure area reached 102 cm(2). Pathological examination identified a thicker epidermis, active angiogenesis and enhanced granulation in group A compared with groups B and C. Using the SP immunohistochemical staining technique, we showed that ESCs in group A were bigger in size and larger in number than in groups B and C. Overall, there was a significant difference in ESCs proliferation and differentiation between group A and group B (or C).</p><p><b>CONCLUSIONS</b>Combination therapy using an alginate dressing and mEGF shows increased proliferation and differentiation of ESCs in patients with refractory wounds compared with those treated with mEGF alone.</p>


Assuntos
Adolescente , Adulto , Animais , Feminino , Humanos , Masculino , Camundongos , Pessoa de Meia-Idade , Adulto Jovem , Alginatos , Usos Terapêuticos , Bandagens , Diferenciação Celular , Proliferação de Células , Fator de Crescimento Epidérmico , Usos Terapêuticos , Células Epiteliais , Biologia Celular , Ácido Glucurônico , Usos Terapêuticos , Ácidos Hexurônicos , Usos Terapêuticos , Imuno-Histoquímica , Queratina-15 , Metabolismo , Células-Tronco , Biologia Celular , Cicatrização
3.
China Journal of Chinese Materia Medica ; (24): 3599-3603, 2012.
Artigo em Chinês | WPRIM | ID: wpr-346899

RESUMO

<p><b>OBJECTIVE</b>To establish an HPLC method for determining nine triterpenes contained in Ganoderma lucidum.</p><p><b>METHOD</b>Chromatography conditions: Alltima C18 (4.6 mm x 150 mm, 5 microm) was adopted as the chromatographic column, with acetonitrile-0.04% formic acid solution as the mobile phase. The detective wavelength was set at 254 nm, and the column temperature was 15 degrees C.</p><p><b>RESULT</b>The linearities of ganoderic acid C2, ganoderic acid G, ganoderenic acid B, ganoderic acid B, ganoderenic acid A, ganoderic acid A, lucideric acid A, ganoderenic acid D, and ganoderic acid C1 ranged between 6.81-40.88, 6.38-38.25, 6.75-40.50, 6.38-38.25, 5.95-35.65, 5.90-35.25, 7.00-42.00, 6.20-37.15 and 6.05-36.4 mg x L(-1) (r = 0.999 4, 0.999 2, 0.999 4, 0.999 2, 0.999 2, 0.994 5, 0.999 0, 0.999 2 and 0.998 4). Their recoveries were 102.1%, 102.3%, 100.6%, 103.3%, 104.1%, 103.2%, 96.42%, 102.5% and 101.5%, with RSD being 1.5%, 0.96%, 1.9%, 1.3%, 1.7%, 2.5%, 0.62%, 2.9% and 1.3%. The content of triterpenes contained in G. lucidum samples from 31 different areas and under different cultivation conditions.</p><p><b>CONCLUSION</b>The method is so feasible and highly reproducible that it can be used for quantitatie determination of the content of triterpenoid acid contained in G. lucidum.</p>


Assuntos
China , Cromatografia Líquida de Alta Pressão , Métodos , Medicamentos de Ervas Chinesas , Reishi , Química , Triterpenos
4.
Journal of Zhejiang University. Medical sciences ; (6): 382-385, 2007.
Artigo em Chinês | WPRIM | ID: wpr-271517

RESUMO

<p><b>OBJECTIVE</b>To explore the relationship between androgen levels and pathological changes of coronary artery in elderly males.</p><p><b>METHODS</b>One hundred and twenty-eight in-patients who received coronary angiography were divided into four groups: single vessel lesion group (SV group), double vessel lesion group (DV group), three vessel lesion group (TV group) and control group. The levels of serum total testosterone (TT) and sex hormone binding globulin (SHBG) were assayed by ELISA, and free testosterone (FT) calculated with the Vermeulen formula.</p><p><b>RESULTS</b>There was significant difference in FT levels among these four groups, while there was no statistical difference in TT levels. FT level in TV group was lower than that in DV group and SV group.</p><p><b>CONCLUSION</b>Serum levels of free testosterone may be correlated with pathological degree of coronary artery.</p>


Assuntos
Idoso , Humanos , Masculino , Pessoa de Meia-Idade , Doença da Artéria Coronariana , Sangue , Patologia , Ensaio de Imunoadsorção Enzimática , Fatores de Risco , Globulina de Ligação a Hormônio Sexual , Metabolismo , Testosterona , Sangue
5.
Journal of Zhejiang University. Medical sciences ; (6): 547-556, 2005.
Artigo em Chinês | WPRIM | ID: wpr-355164

RESUMO

<p><b>OBJECTIVE</b>To observe the relation of androgen levels and atherosclerosis (AS) in elderly males.</p><p><b>METHODS</b>Both carotid arteries and arteries of lower extremity were examined with Doppler ultrasonography. Those with arteriosclerosis and much atheromatous plaque were designated as case group, and those with normal results formed control group. Total testosterone (TT), free testosterone (FT) and estradiol (E2) were measure by radioimmunoassay, HDL-C, LDL-C, TC and TG were assayed by colorimetry, vascular endothelium growth factor (VEGF), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), intercellular adhesion molecule (sICAM-1) were determined by ELISA.</p><p><b>RESULT</b>FT was significantly lower in case group than in control group (P<0.01), no differences were found in TT, E2. HDL-C in control group was higher than that in case group (P<0.01), TC and TG were higher in case group than those in control group (P<0.05). HDL-C was correlated positively and LDL-C was negatively with FT level, while both TC and TG in case group had negative relation with FT. VEGF was higher in case group (P<0.05), and it had negative relation with FT in both groups. TNF-alpha and IL-6 were significantly higher in case group (P<0.05), and they had negative relation with FT. sICAM-1 was significantly lower in control group than it in case group (P<0.01).</p><p><b>CONCLUSION</b>The normal androgen levels, especially FT, have beneficial effect in AS development in elderly males. Low FT level may be an independent risk factor in AS development.</p>


Assuntos
Idoso , Humanos , Masculino , Pessoa de Meia-Idade , Androgênios , Sangue , Aterosclerose , Sangue , Diagnóstico por Imagem , Artérias Carótidas , Diagnóstico por Imagem , Fatores de Risco , Testosterona , Sangue , Ultrassonografia Doppler
6.
China Journal of Chinese Materia Medica ; (24): 677-679, 2005.
Artigo em Chinês | WPRIM | ID: wpr-358098

RESUMO

<p><b>OBJECTIVE</b>To study the chemical constituents of Dracocephalum moldavica.</p><p><b>METHOD</b>The compounds were isolated by using RA polystyrene resin, polyamide and silica gel column chromatography, The structures of the compounds were elucidated on the basis of physic-chemical properties and spectra data.</p><p><b>RESULT</b>Six compounds were identified as syringaresinol4-O-beta-D-monoglucoside (I), sy-ringaresinol-4,4'-O-bis-beta-D-glucoside (II), kaempferol-3-O-beta-D-(6"-O-p-coumaroyl)-galactopyranoside (III), 2"-p-coumarylastragalin (IV), takakin-8-O-beta-D-glucopyranoside (V), beta-daucosterol (VI).</p><p><b>CONCLUSION</b>Compounds I-V were obtained from genus Dracocephalum for the first time.</p>


Assuntos
Galactosídeos , Química , Glucosídeos , Química , Quempferóis , Química , Lamiaceae , Química , Lignanas , Química , Extratos Vegetais , Química , Plantas Medicinais , Química
7.
China Journal of Chinese Materia Medica ; (24): 232-234, 2004.
Artigo em Chinês | WPRIM | ID: wpr-256384

RESUMO

<p><b>OBJECTIVE</b>To study the chemical constituents from the whole plant of Dracocephalum moldavica.</p><p><b>METHOD</b>The compounds were isolated by using column chromatography with RA polystyrene resin, polyamide and silica gel as packing materials, and the structures of the compounds were identified by means of spectral data.</p><p><b>RESULT</b>eight compounds were identified as apigenin(I), luteolin(II), kaempferol(III), isorhamnetin(IV), tilianin(V), agastachoside(VI), acacetin-7-O-(6-O-Malonyl-beta-D-glucopyranoside) (VII) and syringaresinol(VIII).</p><p><b>CONCLUSION</b>Compounds I, II and III were isolated from genus Dracocephalum for the first time and compounds IV, VII and VIII were isolated from Dracocephalum moldavuca for the first time.</p>


Assuntos
Apigenina , Química , Cromatografia em Camada Fina , Furanos , Química , Lamiaceae , Química , Lignanas , Química , Luteolina , Química , Plantas Medicinais , Química
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