RESUMO
Neuroimaging technique is a kind of significant means to explore the mechanism of cerebral plasticity after stroke. Diffusion tensor imaging can be used to describe the structure of white matter fiber bundles and evaluate the degree of damage, but it cannot reflect the functional connections between different brain regions. Task-state functional magnetic resonance (fMRI) can detect the activation of corresponding brain regions caused by specific tasks, but the test design is complex and demanding for subjects. Resting-state fMRI can analyze complex brain networks and reflect functional connections in different brain regions, but the method of data analysis is complex. Functional near-infrared spectroscopy (fNIRS) is another non-invasive method to reflect the functional activation of brain regions, in which temporal resolution is better than fMRI, but the spatial resolution is slightly lower. The combination of multiple detection methods may be an important research direction in the future.
RESUMO
Objective:To observe the effects of transcranial direct current stimulation (tDCS) on the naming of visual and auditory modality in patients with post-stroke aphasia. Methods:From March to November, 2018, 32 patients with post-stroke aphasia were randomly divided into control group (n = 16) and treatment group (n = 16). The treatment group accepted anodal-tDCS (A-tDCS) over left-inferior frontal gyrus (L-IFG) concurrent with speech training, while the control group accepted sham-tDCS. Before and two weeks after treatment, they were assessed with Western Aphasia Battery (WAB), Picture Naming Test and Environmental Sound Naming Test. Results:One patient was lost in the control group. After treatment, Aphasia Quotient of WAB improved in both groups (t > 5.081, P < 0.001), but the difference before and after treatment was not significantly different between two groups (t = 1.550, P > 0.05); the Picture Naming Test score improved in both groups (Z > 2.650, P < 0.01), and the difference before and after treatment was more in the treatment group than in the control group (Z = -2.258, P < 0.05); the object naming score of WAB improved in the treatment group (Z = -3.239, P < 0.01), and the difference before and after treatment was more in the treatment group than in the control group (Z = -3.008, P < 0.01); the score of Environment Sound Naming Test improved in the treatment group (t = -4.745, P < 0.001), and the difference before and after treatment was more in the treatment group than in the control group (t = 2.224, P < 0.05). The scores of spontaneous naming, sentences complement and reaction naming of WAB improved in the treatment group (Z > 2.191, P < 0.05), while the score of spontaneous naming of WAB improved in the control group (Z = -2.376, P < 0.05), but the differences before and after treatment were not significantly different between two groups (Z < 1.568, P > 0.05). Conclusion:A-tDCS over L-IFG may improve the naming ability of visual and auditory modality, which may associate with semantic or phonetic processing.
RESUMO
Objective:To observe the effects of transcranial direct current stimulation (tDCS) on the naming of visual and auditory modality in patients with post-stroke aphasia. Methods:From March to November, 2018, 32 patients with post-stroke aphasia were randomly divided into control group (n = 16) and treatment group (n = 16). The treatment group accepted anodal-tDCS (A-tDCS) over left-inferior frontal gyrus (L-IFG) concurrent with speech training, while the control group accepted sham-tDCS. Before and two weeks after treatment, they were assessed with Western Aphasia Battery (WAB), Picture Naming Test and Environmental Sound Naming Test. Results:One patient was lost in the control group. After treatment, Aphasia Quotient of WAB improved in both groups (t > 5.081, P < 0.001), but the difference before and after treatment was not significantly different between two groups (t = 1.550, P > 0.05); the Picture Naming Test score improved in both groups (Z > 2.650, P < 0.01), and the difference before and after treatment was more in the treatment group than in the control group (Z = -2.258, P < 0.05); the object naming score of WAB improved in the treatment group (Z = -3.239, P < 0.01), and the difference before and after treatment was more in the treatment group than in the control group (Z = -3.008, P < 0.01); the score of Environment Sound Naming Test improved in the treatment group (t = -4.745, P < 0.001), and the difference before and after treatment was more in the treatment group than in the control group (t = 2.224, P < 0.05). The scores of spontaneous naming, sentences complement and reaction naming of WAB improved in the treatment group (Z > 2.191, P < 0.05), while the score of spontaneous naming of WAB improved in the control group (Z = -2.376, P < 0.05), but the differences before and after treatment were not significantly different between two groups (Z < 1.568, P > 0.05). Conclusion:A-tDCS over L-IFG may improve the naming ability of visual and auditory modality, which may associate with semantic or phonetic processing.