Effects of early enteral micro-feeding on neonatal serum Vitamin D levels

Objective: To evaluate the effects of early enteral micro-feeding on neonatal serum vitamin D levels, and to analyze the application value of glutamine

Methods: One hundred ninty neonates enrolled in intensive care unit were randomly divided into a treatment group and a control group [n=95] that were both given enteral and parenteral nutrition support. Meanwhile, the treatment group was fed formula milk containing 0.3 g/[kg·d] glutamine as enteral nutrition support for 14 days

Results: The weight of the treatment group increased significantly faster than that of the control group did [P<0.05]. The treatment group had significantly higher milk amount and calorie intake than those of the control group [P<0.05], and neonates in the treatment group who reached calorie intake of 50/80/100 kcal/kg/d were significantly younger [P<0.05]. Meanwhile, the treatment group was significantly less prone to feeding intolerance than the control group [P<0.05]. After 14 days of feeding, the serum motilin, gastrin and vitamin D levels of both groups all increased, with significant intra-group and inter-group differences. Such levels of the treatment group significantly exceeded those of the control group [P<0.05]

Conclusion: Supplementing early enteral micro-feeding with glutamine promoted the absorption of neonatal routine nutrients and vitamin D, obviously regulated gastrointestinal hormones, and elevated weight as a result

Clinical observation of gammaglobulin therapy for septicemia in premature infants / 中国综合临床

Objective To investigate the therapeutic effects of intravenous gammaglobulin (IVIG) on septicemia in premature infants.Methods The level of sero-IgG was observed in 20 septicemic premature infants before and after IVIG treatment,compared with those of 20 cases without IVIG treatment as controls.Results After IVIG treatment,the level of sero-IgG was remarkably higher than those before IVIG treatment and controls.Conclusion It is suggested that IVIG is safe and effective for treatment of septicemia in premature infants.