Research progresses of biomarkers in early detection of diabetic nephropathy / 中国医师杂志

Although significant progress has been made in the diagnosis and treatment of diabetic nephropathy (DN) patients over the past decades,the mortality rate for DN patients has not been significantly reduced.If effective drug intervention is carried out at the early stage of DN,DN pathophysiological progress will be significantly delayed or hindered.Therefore,it is urgent to develop and apply clinically effective biomarkers for diagnosing early DN.In this paper,biomarkers commonly used in the early detection of diabetic nephropathy and the potential biomarkers involved in the pathogenesis and progression of DN are reviewed.It is expected to provide new ideas and directions for further understanding and development of early biomarkers.