RESUMO
Low birth weight [LBW] is an important public health problem. The problem is prevalent world-wide and has negative impacts. So, its prevention is a major challenge. To determine maternal risk factors of LBW in Cairo city. A case-control, hospital-based, study design. Mothers of 270 LBW neonates were recruited in this study. A control group of mothers of an equal number of normal birth weight [NBW] neonates was chosen. The mothers of LBW and NBW neonates were interviewed using a specially designed questionnaire. All mothers had been subjected to full examinations. The neonates were weighted and examined after labor. Low education, unskilled occupation, and husband unavailability are significant sociodemographic risk factors of LBW; OR=1.75, 1.62, and 2.21, respectively. Mother's height [=145 cm], BMI [<18 kg/m[2]], history of previous abortion, and maternal family history of LBW are significant personal characteristic risk factors of LBW; OR=3.26, 5.11, 3.27, and 3.23, respectively. The significant obstetric risk factors are congenital malformations, weight gain during pregnancy = 6 kg, multiple gestations, bleeding at first/second trimester, presence of complications during delivery, gestation age <37 weeks, and birth spacing <2 years; OR=13.61, 7.61, 7.15, 5.92, 3.93, 3.17, and 2.84, respectively. Absence of antenatal care, inadequate healthy diet intake, physical hard activities, exposure to tobacco smoke, and living nearby heavy air pollution are significant health care behavioral and life-style risk factors of LBW; OR=2.49, 2.72, 2.96, 3.64, and 4.8, respectively. Anemia, hypertension, and history of recurrent chronic/specific infections are significant medical risk factors of LBW; OR=2.68, 4.35 and 4.84, respectively. Anorexia nervosa/stress, oligo/polyhydramnios, and gestational hypertension are significant gynecological/obstetric conditions risk factors; OR=3.53, 3.32, 3.23, and 3.36, respectively. Lastly, the most important risk factors of LBW as weighted by partial F-test are multiple gestations, neonate congenital malformations, weight gain during pregnancy = 6 kg, maternal BMI <18 kg/m][2], gestation age <37 weeks, and mother's weight at early pregnancy = 45 kg, [F test=2.9, 2.7, 2.6, 2.3, 2.2, and 2.2, respectively]. There is a need for improving the quality and utilization of ANC services, nutritional education, birth spacing, and avoidance exposure to tobacco smoke. Also, increasing promotion of reproductive health services in relation to safe motherhood at community level in order to reduce risk factors of LBW is needed. Lastly, further population based studies are needed in different areas in Egypt
Assuntos
Humanos , Feminino , Fatores de Risco , Idade Materna , Idade Gestacional , ParidadeRESUMO
Psoriasis and psoriatic arthritis are common, chronic, immune mediated disease of the skin and joints. Interaction between genes and environment are important in disease causation. The aim of the present study was to determine the socioemographic and clinical characters of adult patients with psoriasis and those with psoriatic arthritis, to define psoriasis and psoriatic arthritis etiological risk factors, and to define the relationship between psoriasis severity and these items. This study was conducted at Dermatology Clinic, Al-Hussein University Hospital. A case-control study design was chosen to perform this research. The study was conducted on 100 adult patients with psoriasis and an equal number of free adults as controls. Criteria for diagnosis of psoriasis and psoriatic arthritis were used. A comprehensive questionnaire was used to survey the studied groups. Body surface area of the affected patients was used as a marker of disease severity. The study showed that 44.0% of the cases had psoriasis age of onset; 22-45 years. Stress was the most common etiological risk factor, 67.0%. While, the most important risk factors were family history of psoriasis, recurrent pharyngitis, smoking >/=20 cigarettes/ day and higher level of education, odds ratio [OR]=7.58, 5.94, 2.78 and 2.69, respectively. Also, 32.0% of the patients had psoriatic arthritis. Psoriatic arthritis comes after psoriasis and had mild severity in 65.6% and 68.7% of the cases, respectively. The most important etiological risk factors were severe psoriasis, smoking >/= 20 cigarettes/day and early onset of psoriasis, OR=9.64, 3.06 and 2.72, respectively. The epidemiology of psoriasis is not well defined in Egypt. The heredity and environmental factors are the most important risk factors. Also, psoriatic arthritis is an important associated disease. The fact that it has no cure has important implications for how it should be viewed, prevented and treated. We recommend that more research should be carried out to understand the true epidemiological features of the disease in Egypt and its impacts on quality of life of the patients