Primary Pulmonary Leiomyosarcoma: A Case Report / 대한흉부외과학회지

The incidence of pulmonary leiomyosarcoma as primary lung tumor is very rare. Most of the primary leiomyosarcomas originate in the hilar region in relation to the main bronchus or pulmonary vessels and only a few originate more peripherally. This rare tumor can mimic bronchial carcinoma and present with local or systemic symptoms, or it may be discovered as an incidental finding on a routine chest X-ray. We report with review of literature, a case of incidental primary pulmonary leiomyosarcoma which originated peripherally. Huge mass was found on the left lung of a 61-year-old man on the chest X-ray peripherally. He underwent the surgical resection of the left pneumonectomy and the postoperative course was uneventful.

Regulation of CC Chemokines in TDI-Induced Nasal Hyperreactive Rats: Expression of RANTES and Eotaxin mRNA Examined Using Competitive PCR / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Chemokines are effective leukocyte chemoattractants and may play an important role in mediating eosinophil recruitment in various allergic conditions in human. Eotaxin is an eosinophil-specific chemokine associated with the recruitment of eosinophils to the site of allergic inflammation. However, it is not yet known as to whether or not RANTES is associated with selective tissue eosinophilia. The aim of this study is to understand the events involved in selective eosinophil migration into inflammatory sites. MATERIALS AND METHODS: We performed the quantitative analysis of RANTES and eotaxin mRNA expression levels in TDI-induced nasal hyper-reactive rats. Expression levels of RANTES and eotaxin mRNA from inferior turbinate mucosa were examined using competitive PCR in 35 experimental rats and 5 control rats compared with infiltrated eosinophil counts. RESULTS: The quantity of RANTES mRNA increased 3 folds 2 day after provocation, and the infiltrating eosinophils were correlated with the expression levels of RANTES mRNA (p<0.01). The quantity of eotaxin mRNA increased 15 folds 1 day after provocation. These results suggest that RANTES and eotaxin play a role in controlling antigen-induced eosinophil recruitment into the tissue. Eotaxin is a more potent and selective chemoattractant for eosinophils than infiltrating eosinophils, and were correlated with the expression levels of eotaxin mRNA (p<0.01). CONCLUSIONS: Further investigations for chemokine receptor related to eosinophils will provide better understanding of the mechanism involved in selective tissue eosinophilia.

Clinical analysis of contact Nd:YAG laser tonsillectomy / 대한이비인후과학회지

No abstract available.

Two cases of Avellis' syndrome / 대한이비인후과학회지

No abstract available.

A case of vascular tinitus treated by transfemoral arterialembolization / 대한이비인후과학회지

No abstract available.

Experimental study of salivary gland stone fragmentation byextracorporeal shock wave lithotripsy / 대한이비인후과학회지

No abstract available.

Clinical Assessment of Gestational Age in the Premature Infant

Recently the clinical estimation of gestational age has been of increasing concern particularly in premature babies because of its great aid in treament and expectation of future health. The clinical distinction between small-for-dates infants and premature babies offers great difficulty, but can be made readily if the gestational age is known. The author has investigated the clinical estimation of gestational age in 100 premature infants who were born at the Seoul National University Hospital, the Eul Ji Hospital and the So Wha Hospital from March to August in 1977, in order to evaluate the correlation between the gestationl age calculated from LMP and the clinically estimated gestaionl age using two charts designed by Brazie and Lubchenco, which were based on 16 physical criteria and 20 neurologic criteria with the following results. 1) The sex and age distribution of the 100 premature infants showed predominance in male and in the 34th336th weeks of gestional age. 2) The numbers of babies whose weight was appropriate, small and large for gestational age were 89, 9 and 2 respectively according to University of Colorado Medical Center Example, while they were 91, 4 and 5 according to the chart based on Rha's report in 1976 in Korea. 3) The correlation percentages between the gestational age determined by each of the 16 physical criteria and those calculated from LMP were as following; vernix (88%), skin and nail plates(88%), recoil-leg(75%), skin thickness appearance(73%), sole creases(68%), genitalia, testes and scrotum(67.5%) and so forth. 4) The correlation percentages between the gestational ages determined by each of the 20 neurologic criteria and those calculated from LMP were as following, pupillary reflex(94%), grasp reflex(90%), vertical positions(87%), head lag (83%), glabellar tap(81%), body extensors(80%), horizontal positions(80%), rooting reflex(80%), and so forth. 5) The correlation coefficiency between the clinically estimated gestational age using the above described two charts and that calculated from LMP was 0.98. And the regression formula for the latter (X) against the former (Y) was Y=0.786X+7.753. With the above results, the author could conclude that clinical estimation of the gestational age with the two charts of Brazie and Lubchenco was highly correlated and it deserves to be recommended for clinical purpose.

Two cases of Cryptococcosis in Children

Cryptococcosis is a subacute or chronic mycotic infection caused by cryptococcus neoformans with a special predilection for the lung, skin and central nervous system, but rarely involving the lymphatic system. Recently the authors have experienced two patients with cryptococcosis in volving the liver and lymph nodes. One was 31/4year old male and the other was 11 year old male. The former had suffered from severe abdominal pain since about 1 month ago and high fever developed 10days before admission. On physical examination, jaundice and hepatomegaly were noted with enlarged and tender lymph nodes in the neck and inguinal region. Bone marrow aspiration revealed increased cellularity with eosinophilia. Lymph node and liver biopsy specimens showed mand granulomas including epithelioid cells and Langhan's type giant cells containing numerous cryptococci. The budding cryptococci were also found in the cerebrospinal fluid prepared with India ink. The latter patient was admitted with the chief complaint of high fever and neck mass which had developed one week ago. On physical examination, enlarged lymph nodes were noted in the neck. But hepatomegaly or splenomegaly was not found. Lymph node bisopsy specimen revealed the same findings with the former case. They were treated with Amphotericin B with some improvement, but as the wre discharged because of poor economic condition the were not sufficiently followed up.