Ultrasonographic assessment of sternoclavicular joint in patient with rheumatoid arthritis

Background: the sternoclavicular [SC] joint is a real diarthrodial joint that can be affected during the route of RA; but, its scientific implications appear to remain under estimated through the rheumatology network. In every day clinical practice, traditional radiography is taken into consideration the usual imaging approach for assessing SC joint involvement; unfortunately, it can constitute a problem inside the diagnostic evaluation because it provides little data regarding gentle tissue involvement. Moreover, it's far much less sensitive than different imaging techniques for assessment of bony abnormalities. Computed tomography [CT] is considered the gold widespread for detection of bone erosions at different joint degrees, inclusive of the SC joint, its major disadvantage is associated with ionizing radiation. The value of magnetic resonance imaging [MRI] is remarkable as it allows identification of bone marrow edema, greater-articular abnormalities, disc and cartilage lesions, and synovial membrane involvement. However, its use is regularly constrained due to its high price. Currently, ultrasound [US] is right extensively common imaging approach in each clinical exercise and in rheumatology studies to visualize joints and tender tissues. To date, there is a regular frame of evidence assisting its validity, reliability, and feasibility inside the evaluation of persistent inflammatory arthritis and its higher sensitivity than scientific exam in the analysis of synovitis, enthesitis, and tenosynovitis in these patients

Aim of the Work: this work aimed to describe the prevalence of sternoclavicular [SC] joint involvement and the relationship between clinical and ultrasound [US] findings in patients with rheumatoid arthritis

Patients and Methods: the ethical approval was obtained from the hospital ethical research committee and each patient participated in this study signed in informed consent. The present study was conducted on a hundred and twenty patients; their age ranged from 20 to 50 years. They were categorized into 2 groups a- 60 patients knowns as RA, b-60 normal control subjects. They were recruited from Physical Medicine, Rheumatology and Rehabilitation Department of Sayed Jalal and Al-Hussein, Al-Azhar University Hospitals, during the period from April 2018 to October 2018

Results: ultrasound revealed a high prevalence of sternoclavicular joint involvement in patients with rheumatoid arthritis than clinical findings

Conclusion: the present study provided US evidence that reveals a higher prevalence of SC joint involvement in patients with RA than in age- and sex-matched healthy controls. US was extra sensitive than medical examination for detecting SC joint involvement in RA. The correlation amongst US synovitis, intraarticular PD and the DAS28 showed that SC joints actively participate within the systemic inflammatory manner of RA. The precise position of US within the assessment of the SC joint in sufferers with RA is but to be mounted firmly in the rheumatologic examination

effect of intraarticular glucocorticoid injection on the serum level of resistin in Osteoarthritis of the knees. Correlation of the level of resisitin to ultrasonographic findings

Background: Osteoarthritis [OA] is one of the ten disabling diseases affecting 9.6% of men and 18 % of women aged over 60 worldwide. OA characterized by articular cartilage loss, subchondral bone remodeling, soft tissue damage and low grade synovitis It is the most common form of arthritis and major cause of disability in the adult population. The main source of resistin in humans is mononuclear cells. Evidence has shown that higher serum levels of resistin in patients with severe OA compared to controls with no OA and resistin are detected in both serum and synovial fluid, proving its systematical and local involvement in inflammatory changes of OA

Aim of the Work: The aim of this work is to study the effect of local GC intra articular injection on the level of serum resistin in OA knees. Also, to study the relation between different serum levels of resistin and US findings of the knee

Patients and Methods: The ethical approval was obtained from the hospital ethical research committee and each patient entering the study will sign an informed consent. Thirty patients with primary knee OA will be recruited for the study from the Physical medicine, 'Rheumatology and Rehabilitation Outpatient Clinic of Al Azhar University Hospitals starting from November 2017 till may 2018. In this study we measure Serum Resistin level and Musculoskeletal ultrasound examination of the knee before and three months after steroid injection

Results: Serum resistin level is markedly decreased after intra articular steroid injection into OA knee joint

Conclusion: Our study revealed that: Resistin could be considered as an important severity marker of knee OA. Serum resistin level is markedly decreased after intra articular steroid injection into OA knee joint. The longer the duration of illness the higher the resistin level. The older the age the higher the resistin level. The longer the duration of illness, the higher the radiological grade. Serum resistin level should be equal to or higher than 2.8 ng / ml to diagnose a case of primary knee OA

prevalence of glucose-6-phosphate dehydrogenase deficiency in people visiting health care center, KFU, Al-Hasa

Objective: To determine the prevalence of G6PD deficiency in people visiting Health Care Center of King Faisal University [KFU], Al-Hasa

Study Design: Observational / Descriptive study

Place and Duration of Study: This study was conducted at the Health Care Center, KFU, Al-Hasa, from August 2014 to April 2015

Materials and Methods: Patients presenting with weakness and anemia were included in the study. Total 214 patients, consisting of 116 children [age 3 to 14 years] and 98 adults [age 15 to 50 years], were screened. The blood samples were analyzed by using [G6P-DH Fluorescence Screening Test]

This kit detects fluorescence under U/V lamp if the sample has G6PD activity

Results: Total 36 [16.8%] of the 214 patients, tested, were deficient for G6PD. Among those deficient patients, 15 [7%] were children [11 males and 4 females], and 21 [9.8%] were adults [13 males and 8 females]. The highest prevalence of G6PD-deficiency occurred among adults, particularly males

Post thyroidectomy hypocalcaemia

To evaluate the incidence and assess the risk factors of hypocalcaemia and permanent hypoparathyroidism following thyroidectomy. 150 patients operated for thyroidectomy from January 2003 to March 2006 were included in this study the fasting serum calcium and phosphorus levels were measured daily before and after surgery until the day of discharge; parathrome measurement was performed for all hypocalcaemic patients. 12 out of 150 patients [8%] developed postoperative hypocalcaemia, 2 of them [16.6%] were considered permanent. Total thyroidectomy was the procedure in 38 patients, 6 from them [15.8%] devoloped hypocalcaemia and the other 6 out of 112 cases[5.4%] were after subtotal thyroidectomy. The hypocalcaemia was 11.4% in toxic goitre [5 out of 44 patients], 12% were malignant goitre[3 out of 12 patients] and 3.6% were simple multinodular goitre [3 out of 84 patients]. When preservation of parathyroid glands and their blood supply is enforced during thyroidectomy, the incidence of postoperative hypocalcaemia and permanent hypoparathyroidism can be consistently deceased