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1.
Chinese Journal of Biochemical Pharmaceutics ; (6): 435-437, 2017.
Artigo em Chinês | WPRIM | ID: wpr-613837

RESUMO

Objective To investigate the clinical treatment of congenital heart disease complicated with infective endocarditis effective programs, joint analysis of the clinical efficacy of the use of antibiotics in surgery on the basis of providing a basis for clinical treatment.MethodsAnalysis of January 2009 to December 2016 in our hospital with congenital heart disease complicated with infective endocarditis clinical data of 78 cases of patients were randomly divided into observation group and control group of 39 cases, The control group was given appropriate antimicrobial treatment, patients in the observation group according to the samples of culture and drug sensitivity test choose appropriate broad-spectrum antibiotics for treatment, observation after treatment and the clinical efficacy of the two groups were analyzed.According to the medical staff were given psychological psychological counseling for patients to explain the importance of disease related knowledge and related treatment, timely eliminate / alleviate the negative emotion of patients with, to ensure that patients with a good attitude to face treatment.Results78 cases of congenital heart disease complicated with infective endocarditis clinical infection germs mainly Staphylococcus aureus and Streptococcus viridans, in addition to a small number of patients infected with Enterococcus faecalis, Staphylococcus epidermidis, gram-negative bacteria and mixed bacteria.Two groups of patients after treatment statistical clinical efficacy results show 56.41% cure rate in patients in the observation group, the effective rate was 97.43% clinical cure rate was 35.90% in the control group of patients, clinical effective rate was 79.49%, a statistically significant difference between groups (P<0.05).Statistical quality of life of patients after two scores, statistics of daily living, psychological feelings, general health, drug dependence and pain and discomfort five indicators, pain and discomfort, and two indicators of the overall health of patients in the observation group was significantly better than the control group (P<0.05), no significant difference.ConclusionThe clinical administration congenital heart infection endocarditis surgical treatment of broad-spectrum antibiotics combined with substantial clinical efficacy, safety, reliability, patients were recovering well, can be clinical.

2.
Chinese Journal of Primary Medicine and Pharmacy ; (12): 15-17, 2016.
Artigo em Chinês | WPRIM | ID: wpr-484345

RESUMO

Objective To study the clinical efficacy of full thoracoscopic lobectomy and thoracotomy in treat-ment of non -small cell lung cancer.Methods 200 patients with non -small cell lung cancer were divided into group A and group B according to the different surgical methods,with 100 cases in each group.Group A was given the full treatment thoracoscopic lobectomy,group B was received treatment thoracotomy.Pain situation were evaluated in visual analog scale(VAS)method,clinical efficacy and adverse reactions of the two groups were compared.Results The intraoperative blood loss,operative time,drainage,VAS scores and hospital stay of group A were (253.4 ± 1.9)mL,(181.3 ±9.3)min,(174.6 ±4.2)mL,(4.2 ±1.4)points and (7.2 ±0.6)d respectively,which were significantly better than (409.3 ±2.4)mL,(232.2 ±3.2)min,(312.9 ±2.5)mL,(6.3 ±0.9)points and (13.5 ± 0.6)d of group B,the differences were statistically significant(t =8.928,9.028,8.232,9.701,10.906,all P 0.05).The incidence of complications of group A were significantly lower than those of group B,the difference was statistically significant(χ2 =9.033,P =0.002). Conclusion Full thoracoscopic lobectomy in the treatment of non -small cell lung cancer has better effect compared with thoracotomy,its harm to patients is small,and has fewer postoperative complications.

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