Levosulpiride in premature ejaculation

Premature ejaculation is one of the most common sexual disorders. A large number of treatment options have been used so far for the treatment of this dysfunction and still a large number of experts are doing research in this field. Here we have tried to research on the beneficial effects of levosulpiride in the treatment of PE. Eighty-eight patients form different areas of Hazara division suffering from PE were chosen. Sixty-four patients were given levosulpiride and the remaining 24 patients were given Placebo. Out of 64 patients who have been given levosulpiride, 30 patients showed very good improvement, 14 patients showed some improvement, 14 patients showed little and 06 patients showed no improvement. levosulpiride have very good beneficial effects in the treatment of PE

Presentation of typhoid fever patients in Hazara division and response to different treatment regimens

Response to treatment can vary in patients with typhoid fever. This study was carried out on a group of typhoid patients who were treated in Medical 13 ward of Ayub Teaching Hospital. Resistance to antibiotic is commonly acquired by Salmonella typbi and is widely reported. Objective of study was to identify such resistance in patients coming from parts of Hazara Division. All patients vv ho presented with typhoid lever and admitted to Medical 13 Unit from 1st July to 30th September 2002 were included in study. Out of 76 patients 46 [60%] were male. Epidemiological [late, presenting symptoms, finding on physical examination, laboratory investigation and radiological examination were recorded. Then one of six commonly used treatment regimens were started. Response to treatment was studied. Common presenting symptoms and signs were recorded. Headache and fever were seen in 100% of patients. Cough and hypotension were among presenting features in 65% of patients. Lcucocyte count of Less than 4x1000/dl was seen in 11%] of samples. Liver functions and Renal function were found alterd ill 30% of patients. Study of response pattern to different regimens suggested relatively poor response to tlouroquinolones. Fever of those patients who were treated with cbloampbenicol and cefexime settled early as compared to patients on other regimens. Conclusions. In addition to well known presenting features of typhoid like headache, fever, cough, hypotension and leueopenia abnormalities of renal and liver functions were commonly seen. Response to quinolone was poor suggesting emergence of resistance of salmonella typhi in this area