Intrauterine Femur Fracture in Premature Neonate-A Case Report / 대한주산의학회잡지

Intrauterine fracture in a neonate is rare but can occur without trauma to the mother and can be caused by genetic factor or external pressure, or skeletal disorder. Authors experienced a case of intrauterine femur fracture in a female premature patient which was discovered at birth. The patient was born at 28+3 weeks by a cesarean section. Her birth weight was 900 g. Amniotic fluid was clear and there was no amniotic membrane adhesion. The mother was 31 years old and had preeclampsia but had no other previous medical history. She had no experience of trauma in daily activities and abnormal findings during antenatal care. On x-ray finding taken after birth, there was callus formation at the epiphysis of the right distal femur. We found no shortening of the limbs during physical examination of the neonate but there were edematous change at the distal portion of the right thigh. She had no neurologic abnormality. We report a case of intrauterine femur fracture with no special history in the mother.

Intrauterine Femur Fracture in Premature Neonate-A Case Report / 대한주산의학회잡지

Intrauterine fracture in a neonate is rare but can occur without trauma to the mother and can be caused by genetic factor or external pressure, or skeletal disorder. Authors experienced a case of intrauterine femur fracture in a female premature patient which was discovered at birth. The patient was born at 28+3 weeks by a cesarean section. Her birth weight was 900 g. Amniotic fluid was clear and there was no amniotic membrane adhesion. The mother was 31 years old and had preeclampsia but had no other previous medical history. She had no experience of trauma in daily activities and abnormal findings during antenatal care. On x-ray finding taken after birth, there was callus formation at the epiphysis of the right distal femur. We found no shortening of the limbs during physical examination of the neonate but there were edematous change at the distal portion of the right thigh. She had no neurologic abnormality. We report a case of intrauterine femur fracture with no special history in the mother.

Comparison of neonatal outcomes between the spontaneous and in vitro fertilization twin pregnancies / 소아과

PURPOSE: There is a dominant opinion that in vitro fertilization (IVF) leads to an increased incidence of twins, low birth weight (LBW) infants, prematurity and mortality. On the other hand, technical development of IVF and improvement of neonatal intensive care have increased the survival rate of neonates. The purpose of this study was to verify the tendency by comparing the clinical aspects of IVF and spontaneously conceived twins, and to establish methods to increase the survival rate of neonates after IVF. METHODS: Retrospective reviews were performed on all twin infants who were admitted to the nursery and NICU at Kangnam Sacred Heart Hospital, Hallym University from January 1, 2000 to December 31, 2006. Medical records of IVF twins (study group, n=92) and spontaneously conceived twins (control group, n=265) were analyzed and compared. Neonatal outcomes and complications, as well as obstetric outcomes, were analyzed and compared. RESULTS: Mean gestational age and birth weight of the study group (34.6+/-3.5 weeks, 2,203.9+/-617.2 g) were considerably lower than those of the control group (36.3+/-2.4 weeks, 2,367.0+/-517.9 g). The frequency of prematurity less than 37 weeks (68.5% vs 51.3%) and extremely LBW (15.2% vs 6.4%) were also significantly higher in the study group. Other neonatal outcomes were all insignificant. The obstetric characteristics, maternal age (32.6+/-3.3 years vs 30.3+/-3.9 years) and the frequency of cesarean delivery(95.7% vs 79.9%) were significantly higher in the study group. Other obstetric outcomes were insignificant except for the frequency of incompetent internal os of cervix (36.2% vs 3.6%) and cerclage operation (38.3% vs 4.3%). CONCLUSION: Based on the above results, clinical outcomes of twin infants will be further improved by careful attention and thorough antenatal care of the IVF twins.

Basal cell nevus syndrome (gorlin syndrome) confirmed by PTCH mutations and deletions / 소아과

Basal cell nevus syndrome (BCNS), also known as Gorlin syndrome, is a rare autosomal dominant disorder characterized by variable manifestations, including multiple basal cell carcinomas, odontogenic keratocysts of the jaw, skeletal anomalies including scoliosis and bifid ribs, palmar and plantar pits, calcification of the falx cerebri, and biparietal frontal bossing. We report a case of a 9-year-old boy with the clinical features of basal cell nevus syndrome, in which a PTCH gene mutation was confirmed by DNA testing.