The validity of uro-cytogramme in the diagnosis of real premature puberty of young girls

Urocytogramme was made for study on 97 female pediatric children at the Pediatric Endocrinology Department of Renne Centre of Hospital and University – France. 49 cases were determined as early puberty and 48 cases were not puberty. Girl with the early development of breast, with or without other pubertal signs, having an urocytogramme of stimulated form of IK>6, IK>3, number of surface cells S>6 was determined as true early puberty. The examination was easy to make with low cost, no blood taken, the girl had not to hospitalize.