A case of congenital smooth muscle hamartoma / 대한피부과학회지

No abstract available.

Comparative Study for the Comedolytic Effects of Several Topical Acne Remedies on Experimentally Induced Comedones in Rabbits / 대한피부과학회지

No abstract available.

Two Cases of Primary Cutaneous Cryptococcosis / 대한피부과학회지

We report two cases of primary cutaneous cryptococcosis that is a very rare disease. One patient was a 45 year-old female, who had had an erythematous hard nodule on dorsum of right wrist for ten months, The other patient was a 53-year-old male, who had had itching and burning erythematous rashes on left auricle for ten months. Histopathologic examination showed typical spores with capsules, Other physical examination and laboratory findings were within nomal limit. Our patients were successfully treated with excision and combination of amphotericin B and 5-fluoro-cytosine.

An Electron Microscopic Study on the Effect of Vitamin A Acid on Experimentally Induced Comedones in Rabbit / 대한피부과학회지

Comedones were induced at external ears of rabbits by daily application of 50% oleic acid in paraffin oil for 3 weeks. 13 cis-retinoic acid(RA) solution(0.1%)wae apllied to experimentally induced comedones. The morphologic changes around the epithelial lining of comedones were observed by transmission electron microscopy to define the effect of RA on comedones. In follicles treated with RA, the results were summarized as follows: l) The thickness of the stratum corneum of the epithelium was markedly decreased with widening of intercellular spaces. 2)The number of desomosomes and desmosoma1 bodies between horny cells was decreased. 3) Abnormally appeared tight junction in the stratum corneum and disappearance of membrane coating granules in the straurn granulosum were reversed to normal state, disappearance of tight junction and increment of membrane coating granule respectively by the application of RA. These observations suggest that RA has comedolytir. effect by decreasing cohesive- ness between horny cells.

Two Cases of Angiosarcoma / 대한피부과학회지

We present two cases of angiosarcoma occuring on the scalp of aged person. The case 1 was a 74 year-old male who have had purplish colored, slightly raised irregular surfaced plsque on frontal scalp. The other case was a 69-year-old man who have had purplish nodule with satellite lesions on the right frontal area. The cases were confirmed by clinical picture, histologic findings. Treatment was not done because of refuse by patient.

A Case of Multiple Cutaneous Leiomyoma / 대한피부과학회지

We present a case of multiple cutaneous leiomyoma in a 45 year old woman. About 20 years ago, multiple skin colored papules developed on right cheek and man4ibular area. About 10 years after the onset of the disease a uterine myoma developed which wae tree,ted by total hysterectomy. The skin lesions were gradually increasing in number and size, Some larger nodular lesions changed to brown in color and became painful after cold exposure. The histopathologic finding showed typical leiomyoma arieing from arrector pilorum muscle.

A Case of Follicular Occlusion Triad / 대한피부과학회지

A case of "Follicular Occlusion Triad" associated with acne conglobata, hidradenitis suppurativa and perifolliculitis capitis abscedens et suffodiens in 40-year-old male patient is presented with brief review of literature. Widespread acne occured on the face k upper back at the age of 16. Several years later, firm & tender erythematous poorly demarcated nodules developed on the back, buttock and axilla. Also, erythematous nodules developed on temporooccipital area of the scalp. Thereafter, the skin lesions become fluctuant cystic. Some of the skin lesions healed leaving severe hypertrophic scars, and purulent materials expressed from some of persistent lesions. The patient was trested with systemic 13-cis-retinoic acid, antibiotics, corticosteroids injection and incision & drainage with considerable improvement.

A clinical study of topical mucopolysaccharides and polydeoxyribonucleoprotein (Foltene) therapy in alopecia

We performed clinical trials to evaluate the therapeutic effects of Foltene in patients of the several types of hair fallings. Thirty patients with male pattern baldness, alopecia areata and seborrheic alopecia were included in this study. Foltene was applied every other day for 40 days, and followed by maintenance therapy of twice application a week. The duration of whole therapy was 6 months. We conclude that Foltene is an effective and agent for male pattern baldness, alopecia areata and seborrheic alopecia from the following results. Ten patients with male pattern baldness was treated with Foltene for 6 months. Foltene had therapeutic effects of 50% in hair regrowth, 70% in decreased hair falls, 30% in decreased dandruff, 50% in decreased seborrhea. Thirteen patients with alopecia areata was treated with Foltene for 6 months. Foltene had therapeutic effects of 61.6% in hair regrowth, 53.9% in decreased in hair falls, 53.9% in decreased dandruff, 77.0% in decreased seborrhea. Seven patients with seborrheic alopecia was treatment with Foltene for 6 months. Foltene had therapeutic effects of 85.8% in hair regrowth, 57.2% in decreased hair falls, 42.9% in decreased dandruff, 85.8% in decreased seborrhea. The degree of therapeutic success was related to the duration of therapy. The side effects were as followed: itching sensation developed in 2 patients (6.7%); tingling sensation in 3 patients (10.0%); burning sensation in 1 patient (3.3%); erythema in 3 patients (10.0%).

A Case of Linear Porokeratosis / 대한피부과학회지

Linear porokeratosis is a rare variant of porokeratosis and usually occurs in childhood. A 37-year-old female is presented with linear porokeratosis on the posterior aspeet of the right lower extremity exhibiting the classical histopathologic criteria of the disease. Treatment with an oral etretinate resulted in a remission of the lesions.

A Case of Trichilemmoma on the Scalp / 대한피부과학회지

Tricilemmoma is a benign, solitary tumor that may be clinically misdiagnosed as basal cell carcinoma or verruca. It affects frequently the face of elderly rnen. We present herein a case of trichilemrnoma in a 70-year-old Korean wornan who had a slowly growing tumor on the scalp for 50 years. The histopathologic findings revealed lobular acanthosis of glycogeri rich clear cells and palisade of columnar cells resting on prominent basement membrane.

A Case of Apocrine Hidrocystoma Occurring in the Female Genitalia / 대한피부과학회지

A 31-year-old female patient has had a translucent cystic papule on the genitalia since 2 years ago. The diagnosis was confirmed by clinical and histopathological findings. This is the rare case of apocrine hidrocystoma occring in the fernale genitalia in the literature.

Effect of Sulfhydryl Compounds on Melanosomal Morphology of Epidermal Melanocytes in UV - Irradiated Black Mice / 대한피부과학회지

The present study was performed to evaluate the effect of sulfhydryl compounds, cysteine and glutathione, on the size of melanosomes and the ratio of melanosormai stages of epidermal melanocytes in UV-irradiated black mice. The results were as follows; 1. Both of cysteine and glutathione showed significant diminution in the short axis of melanosomes and the percentage of stage 4 melanosomes of epidermal melanocytes in C57BL black mice skin. 2. The length of short axis of melanosomes in glutathione-treated group is smaller than those in cysteine-treated group at the end of 3rd week of intraperitoneal injection. The percentage of stage IV melanosomes significantly decreased in glutathione-treated group and cysteine-treated group at the end of 3rd week and 5th week respectively. 3. In glutathione-treated group, the short axis of melanosomes and the percentage of stage 4 melanosomes both decreased in proportional to the period of intraperitoneal in]ection.

A Case of Multiple Trichoepithelioma / 대한피부과학회지

A 33-year-old man had multiple, dome shaped, pin-head sized, hard papules on the center of face and pigeon's egg sized hard tumors on the left upper arm and the trunk. The histopathological findings of the skin biopsy specimens from face and left upper arm showed tumor islands composed of basophilic cells of the same sppearance as basalioma cells, arranged in a lacelike and solid aggregates, without horn cysts.

A Case of Friction Melanosis / 대한피부과학회지

Friction melanosis is frequently developed in thin, young woman, on thc covered skin of spinc, rib, elbow, knee and tibia. These lesions range from brown to rcddish-brown in color, appear in either band shapes or reticular patterns, and exhibit no overt syrnptoms. They do not show any inflamatory changes, and the skin remains smooth. According to histopathological findings, the main changcs arc perivascular melanophages on the papillary derrnis and upper dermis, and also increased melanin granules on the basal layer. The following case concern a relatively thin 20-year-o1d female patient. She had a syrwptoniless brown color changcs above the ribs of back, growing in dircction of the ribs for a period of three years. This change was band shaped, but there were no signs of inflammatory reaction, leaving the skin smooth. A biopsy was performed on the relevant tissue, and clinical-histopathological analysis was resulting in diagnosis of friction melanosis.

Cutaneous metastatic adenocarcinoma of stomach : nodular and inflammatory carcinoma

A 65-year-old male patient presented multiple cutaneous nodules on trunk and an erythematous inflammatory lesion resembling erysipelas on left side of neck. Result of skin biopsies disclosed groups of metastatic adenocarcinoma cells in the dermis, subcutaneous tissue, and lumina of the lymphatic vessels. Histopathologic examination of the stomach, along with the gastroscope, established that the cutaneous metastasis was of stomach origin.

An Epiderniological Study of Contact Dermatitis: I . Multicenter Trials / 대한피부과학회지

The present work is the first joint epidermiological study of contact dermatitis carried out by the Korean Contact Dermatitis Research Group which was organized in 15i8p. For the past 2 years total 937 patients with contact dermatitie and suspected contact dermatitis have been routinely patch tested with Hollister-Stier standard battery (28 different antigens) by using Finn Chamber at 10 different General Hospitals which were located around Seoul area. The MOHL index was quite different from the western data, which was characterized with less male, rare leg ulcer and less occupational cases. However, housewife hand eczema cases were more common. The most common senaitiaers were ammoniated mercury, nickel sulfate, potassium dichromate, cinnamic alcohol, neomycin sulfate, paraphenylendiamine, balsam of Peru and thimerosal in order of frequency.

Two Cases of Eccrine Spiradenoma / 대한피부과학회지

She describe herein two cases of eccrine spiradenoma. One is an indolent and the other is painful or tender multiple small nodules distributed in a zosteriform pattern. Histopathologically, the encapsulated lobules of the tumor are composed of two types of cells, intensely staining cells and pale staining cells, usually arranged in whorls, cords, and pseudoglands. In the second case, enzyme histochemical staining and electron microscopic examination have been done and are compared with other cases in the literature.

A Case of Allergic Vasculitis Associated with Chronic Active Hepatitis / 대한피부과학회지

Hepatitis B virus is of growing clinical importance. This virus not only produces acute and chronic liver disease but also produces a variety of dermatologic syndromes. A 77-year-old man with erythematous urticarial-like papulonodules had a chronic active hepatitis. And microscopic findings were compatible with allergic vasculitis. We reported a case of allergic vasculitis associated with chronic active hepatitis and reviewed literatures briefly.

Epidermal Changes with Ultraviolet Irradiation and PUVA Treatment in the Black Mouse / 대한피부과학회지

The pretent study was performed to study the epiderrnal changes of ultraviolet irradiation and PUVA treatment in the black mice. The following results were obtained: 1) The histologic changes of the epidermis, number of DOPA positive melanocytes and ultrastructural changes of keratinocytes due to UVB and PUVA were rnore prominent than those of UVA irradiation. 2) The histological changes after 8-MOP photosensitization closely mirnic those of UVR irradiation, and constant, finding was hyperkeratosis. 3) Early histological change after UVL irradiation & IUVA treatment was appearance of dytkeratotic cells. 4) Pro]onged exposure to UVB & PUVA resulted in transient epidermal hyperplasia, and epidermal atrophy occurred 3 weeks after PUVA treatment. 5) Early electron microscopic changes was perinuclear edema, juxtanuclear vacuoles and clumping of tonofilament.

Acquired , Bilateral Nevus of Ota - like Macules : A Clinical and Histopathological Observation / 대한피부과학회지

We observed the clinical and histopathologic characteristics of acquired, bilateral nevus of Ota-like macules in each 80 and 23 patients. The results were as follows: 1. All patients were female and the peak age of onset was third decade with an a,verage age of 27.4 years. 2. The colors of lesions were slate, brown, dark brown, and blue black in order of freguency. 3. The lesions were most comrnonly observed in the malar area and alae nasi. 4. Three patients had family history of acquired, bilateral nevus of Ota-like :macules. 5. Histopathologically pigment-bearing cells, bipolar or irregular in shape, were found mostly in the upper- and mid-portion of the dermis. The melanocytes showed weakly positive dopa reaction. 6. In electron microscopic observation, these pigrnent-bearing cells contained many singly dispersed melanosomes in stage 3 and 4 of melanization and wece surrounded by an extracellular sheath.