A Case of Pancreatic Metastasis From a Papillary Thyroid Carcinoma Mimicking Pancreatic Cancer / 대한내과학회지

Papillary thyroid cancer (PTC) has a good prognosis and a low incidence of distant metastases. It is extremely rare for PTC to metastasize to the pancreas. Only five cases have been previously reported worldwide. Most cases are discovered incidentally by abdominal computed tomography (CT) or positron emission tomography-CT (PET-CT) during follow-up studies after thyroidectomies. Pancreatic metastasis of PTC is usually unidentifiable by a whole-body I131 scan, a common follow-up modality. When a pancreatic mass is found in patients with PTC, it must be differentiated from pancreatic cancer. In previous reports, patients with pancreatic metastases of PTC underwent operations for therapeutic diagnosis or underwent fine needle aspiration biopsies (FNAB). However, it is unclear whether the benefit of an operation outweighs the risk. We experienced a case of PTC with pancreatic metastasis that was found on PET-CT. Contrast-enhanced endoscopic ultrasonography (EUS) was performed to evaluate the characteristics of the pancreatic mass and pathological confirmation was obtained cytologically via EUS-FNA.

Inflammatory Responses in the Muscle Coat of Stomach and Small Bowel in the Postoperative Ileus Model of Guinea Pig

PURPOSE: Small intestinal function returns first after surgery, and then the function of the stomach returns to normal after postoperative ileus (POI). The aim of this study was to investigate inflammatory responses in the muscle coat of stomach and small intestine in guinea pig POI model. MATERIALS AND METHODS: The distance of charcoal migration from pylorus to the distal intestine was measured. Hematoxylin and eosin (H&E) and immunohistochemical stain for calprotectin were done from the histologic sections of stomach, jejunum and ileum obtained at 3 and 6 hour after operation. Data were compared between sham operation and POI groups. RESULTS: The distance of charcoal migration was significantly reduced in the 3 and 6 hour POI groups compared with sham operated groups (p<0.05). On H&E staining, the degree of inflammation was significantly higher in the stomach of 3 hour POI groups compared with jejunum and ileum of POI groups or sham operated groups (p<0.05). Calprotectin positive cells were significantly increased in the muscle coat of stomach of 3 hour POI groups compared with jejunum and ileum of POI groups or sham operated groups (p<0.05). There was strong association between the degree of inflammation and calprotectin positive cells in stomach. CONCLUSION: Postoperative ileus induced by cecal manipulation significantly increased the degree of inflammation and calprotectin positive cells in the muscle coat of stomach as a remote organ. The relevance of degree of inflammation and the recovery time of ileus should be pursued in the future research.

Magnet Compression Anastomosis for Bilioenteric Anastomotic Stricture after Removal of a Choledochal Cyst: A Case Report / 대한소화기내시경학회지

Magnet compression anastomosis is a nonsurgical method that uses two magnets to treat bilio-biliary and bilio-enteric anastomotic strictures after a living donor transplantation. The compression pressure of the two magnets induces ischemic necrosis at the anastomostic stricture and creates a fistula at the stricture site. A choledochal cyst is an uncommon congenital anomaly characterized by dilatation of the biliary tree and can cause obstructive jaundice, cholangitis, biliary stones, and cholangiocelluar carcinoma. Treatment for choledochal cyst is essentially surgical including total excision of the cyst with hepaticoenterostomy, but there can be complications such as postoperative intrahepatic stones and recurrent cholangitis due to a stricture at the site of the anastomosis. Endoscopic and fluoroscopy-guided radiologic interventions can be applied to resolve the anastomotic stricture, and re-operation is possible as the method of last resort. We report here a first case, trial magnet compression anastomosis in Korea of a bilioenteric anastomotic stricture after excision of a choledochal cyst and hepaticojejunostomy.

Endoscopic botulinum toxin injection in cricopharyngeal dysphagia / 대한내과학회지

Botulinum toxin has been used to treat various gastrointestinal tract diseases such as achalasia, diabetic gastroparesis, sphincter of oddi dysfunction, and chronic anal fissures. Recently, it has also been used for the treatment of cricopharyngeal muscle dysfunction. Several studies have reported that botulinum toxin injections may be a safe and effective treatment. Previously, cricopharyngeal muscle dysfunction was treated by mechanical balloon dilation or cricopharyngeal myotomy. Here, we report a case of a 57-year-old man who presented with cricopharyngeal dysphagia due to cerebral infarction and who was successfully treated with endoscopic botulinum toxin injection.

A Case of Malignant Rhabdoid Tumor in the Anterior Mediastinum / 결핵및호흡기질환

Malignant rhabdoid tumors arise primarily from the kidney. Extrarenal malignant rhabdoid tumors are rare, with the liver, central nervous system, and skin reported as the primary sites. Malignant rhabdoid tumors of the mediastinum are extremely rare among extrarenal malignant rhadoid tumors; only 3 cases have been reported to date, all characterized by aggressive clinical behavior. We experienced a 35-year-old woman diagnosed with malignant rhabdoid tumor in the anterior mediastinum with multiple metastases. The tumor was surgically unresectable, and treated with palliative radiation therapy. Three-month after radiation treatment, she died from dissemination of the malignant rabdoid tumor.

Hematochezia with Colonic Polypoid Angiodysplasia in a Young Female Patient

A 18-year-old girl visited the hospital due to hematochezia. Colonoscopy revealed a 6-mm Yamada type II polyp with stigmata of bleeding, and a shallow ulcer on top was found at the cecum base. The polyp was removed by snare polypectomy, and hematochezia stopped thereafter. Angiodysplasia was diagnosed histopathologically. Generally, angiodysplasia appears as a flat or elevated, bright-red lesion on endoscopy, with a polypoid shape being extremely rare. This case is significant because the lesion occurred at the youngest reported age and was the smallest that has been reported, and is the only polypoid arteriovenous malformation to be discovered in the cecum.

A Case of Pheochromocytoma Presented with Severe Left Ventricular Dysfunction Combined with Cardiogenic Shock after Caesearian Section Delivery Responding to Treatment of Extracorporeal Membrane Oxygenation

Peripartum cardiomyopathy has rarely been reported in the presence of pheochromocytoma. We report a case of 18-year-old female, who presented with cardiogenic shock at postpartum period. After extracorporeal membrane oxygenation, her cardiopulmonary function improved. She was diagnosed with peripartum cardiomyopathy, thereafter 24hr urine study and abdomen CT was compatible with pheochromocytoma. The adrenal mass was surgically removed without complications.

A Case of Pheochromocytoma Presented with Severe Left Ventricular Dysfunction Combined with Cardiogenic Shock after Caesearian Section Delivery Responding to Treatment of Extracorporeal Membrane Oxygenation

Peripartum cardiomyopathy has rarely been reported in the presence of pheochromocytoma. We report a case of 18-year-old female, who presented with cardiogenic shock at postpartum period. After extracorporeal membrane oxygenation, her cardiopulmonary function improved. She was diagnosed with peripartum cardiomyopathy, thereafter 24hr urine study and abdomen CT was compatible with pheochromocytoma. The adrenal mass was surgically removed without complications.

Regulation of cementoblast differentiation and mineralization using conditioned media of odontoblast / 대한치주과학회지

For the regeneration of periodontal tissues, the microenvironment for new attachment of connective tissue fibers should be provided. At this point of view, cementum formation in root surface plays a key role for this new attachment. This study was performed to figure out which factor promotes differentiation of cementoblast. Considering anatomical structure of tooth, we selected the cells which may affect the differentiation of cementoblast - Ameloblast, OD11&MDPC23 for odontoblasts, NIH3T3 for fibroblsts and MG63 for osteoblasts. And OCCM30 was selected for cementoblast cell line. Then, the cell lines were cultured respectively and transferred the conditioned media to OCCM30. To evaluate the result, Alizarin red S stain was proceeded for evaluation of mineralization. The subjected mRNA genes are bone sialoprotein(BSP), alkaline phosphate(ALP), osteocalcin(OC), type I collagen(Col I), osteonectin(SPARC ; secreted protein acidic and rich in cysteine). Expression of the gene were analysed by RT-PCR. The results were as follows: 1. For alizarin red S staining, control OCCM30 didn't show any mineralized red nodules until 14 days. But red nodules started to appear from about 4 days in MDPC-OCCM30 & OD11-OCCM30. 2. For results of RT-PCR, BSP mRNAs of control-OCCM30 and others were expressed from 14 days, but in MDPC23-OCCM30 & OD11-OCCM30 from 4 days. Like this, the gene expression of MDPC23-OCCM30 & OD11-OCCM30 were detected much earlier than others. 3. For confirmation of odontoblast effect on cementoblast, conditioned media of osteoblasts(MG63) which is mineralized by producing matrix vesicles didn't affect on the mineralized nodule formation of cementoblasts(OCCM30). This suggest the possibility that cementoblast mineralization is regulated by specific factor in dentin matrix protein rather than matrix vesicles. Therefore, we proved that the dentin/odontoblast promotes differentiation/mineralization of cementoblasts. This new approach might hole promise as diverse possibilities for the regeneration of tissues after periodontal disease.

The inter-relationship between the pain and urinary tract calculi / 대한비뇨기과학회지

The severe pain of the urogenital organ may arise not only from other various diseases, but especially from the urinary tract calculi which present the characteristic pain. We must differentiate the pain from the calculi and other diseases for the patients who department of urology. The differential diagnosis must be made under consideration of the findings of physical examination and urinalysis, but simple K.U.B. and I.V.P. have the absolute diagnostic value among the patients who complain of the characteristic pain due to the urinary tract calculi. The author have studied the relationship between the pain and urinary tract calculi and have the following result. 1) 132(67.O%) urinary tract calculi among total 197 cases who complain of the pain. 2) 37(56.9%) urinary tract calculi among 65 cases who complain of dull pain. 3) 70(72.8%) urinary tract calculi among 96 cases who complain of colicky pain. 4) 25(69.4%) urinary tract calculi among 36 cases who complain intermittent colic and dull pain.

A Case Report of Urethral Fistula due to Vesical Calculi / 대한비뇨기과학회지

Urethral fistula due to vesical calculi is very rare in urological field.We are presenting a case of urethral fistula due to vesical calcula along with article review.

Clinical Observation on the Varicocele / 대한비뇨기과학회지

Varicocele is a common Disease entity in urological field There are considerable number recurrent after either surgery or conservative treatment, also even sterility in bilateral case. The author has experienced 55 cases of varicocele at C.A.F.G.H. in one near period. In 10 mild cases, the only scrotal elevation were applied, and in the other severe 45 cases were undergone surgery. 5 cases in each were revealed recurrent respectively.

A Case Report of Rhabdomyosarcoma Originating from the Prostate / 대한비뇨기과학회지

Rhabdomyosarcoma is a very rare case in urological field. We have experienced a case of rbabdomyosarcoma originating from the prostate. So we present this case report with the article review.

A Case Repart of Interstitial Cystitis / 대한비뇨기과학회지

No abstract available.