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Objective@#This study’s objective is to assess the efficacy and safety of Pulsed Magnetic Therapy System (PMTS) in improving insomnia disorder. @*Methods@#Participants with insomnia disorder were randomly assigned to receive either PMTS or sham treatment for four weeks (n= 153; PMTS: 76, sham: 77). Primary outcomes are the Insomnia Severity Index (ISI) scores at week 0 (baseline), 1, 2, 3, 4 (treatment), and 5 (follow-up). Secondary outcomes are the Pittsburgh Sleep Quality Index at baseline and week 4, and weekly sleep diary-derived values for sleep latency, sleep efficiency, real sleep time, waking after sleep onset, and sleep duration. @*Results@#The ISI scores of the PMTS group and the sham group were 7.13±0.50, 11.07±0.51 at week 4, respectively. There was a significant group×time interaction for ISI (F3.214, 485.271=24.25, p<0.001, ηp 2=0.138). Only the PMTS group experienced continuous improvement throughout the study; in contrast, the sham group only experienced a modest improvement after the first week of therapy. At the end of the treatment and one week after it, the response of the PMTS group were 69.7% (95% confidence interval [CI]: 58.6%–79.0%), 75.0% (95% CI: 64.1%–83.4%), respectively, which were higher than the response of the sham group (p<0.001). For each of the secondary outcomes, similar group×time interactions were discovered. The effects of the treatment persisted for at least a week. @*Conclusion@#PMTS is safe and effective in improving insomnia disorders.
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Objective:To analyze of hot spots and cutting-edge dynamic researches on Traditional Chinese Medicine (TCM) treatment for atopic dermatitis (AD).Methods:The data were abstracted from the literature of AD from CNKI, VIP and WanFang database, during January 1st, 2000 to May 31st, 2021. CiteSpace was used to map Knowledge and visualize information on the law, research hot spots and trendency of TCM in the treatment of atopic dermatitis in recent 20 years.Results:A total of 478 articles were included, mainly from TCM colleges and universities in various provinces. Most of the cooperative institutions have subsidiary relationships, and there is less cross-agency and cross-regional cooperation. Hot research topics included AD, clinical research, TCM therapy, TCM syndrome differentiation, compound Glycyrrhizin, TCM external treatment, and TCM formular, forming 8 main clusters. Integrated Traditional Chinese and Western Medicine was the developing trend in the treatment of AD, and the establishment of animal models to evaluate the therapeutic effect is the research frontier.Conclusion:Knowledge mapping can show the evolution path, research hotspot and frontier of TCM in the treatment of AD, and lay a foundation for high quality researches.