Lichen planus along with blaschko lines "blaschkoian lichen planus"

To compare the characteristics of Blaschkoian lichen planus with typical lichen planus. In this case series, we diagnosed 7 patients of Blaschkoian lichen planus [3 males and 4 females] based on specific clinical presentation, histopathological findings and exclusion of other dermatologic disease mimicking Blaschkoian lichen planus. Of 7 patients, 4 [57.1%] had middle to senile age, without involvement of the buccal mucosa, nails and scalp. Involvement of both trunk and lower extremity were seen in one patient. Unilateral lichenoid skin lesion with specific configuration were located on trunk in 6 [85.7%] cases, forehead in 1 [14.3%] and on lower extremity in 1 [14.3%] case. One [14.3%] patient had history of troublesome pruritus. Although diagnosis of typical lichen planus is uncomplicated but in Blaschkoian lichen planus absence of prominent pruritus, different configurations of skin lesion on each site of the body without involvement of buccal mucosa may pose problems in diagnosis. We recommend further studies with large number of Blaschkoian lichen planus to find out more about clinical manifestations

Case report of a histoid leprosy patient

Histoid leprosy is one of the rare kinds of lepromatous leprosy with specific clinical pathologic manifestations. It is most commonly observed in patients who have been under long-term single drug therapy with dapsone. Clinical manifestations mostly consist of red papules and nodules and pathologic examination there are spindle like histiocytes. Following acid-fast staining, abundant bacilli can be seen. Significance of these patients is due to their rarity, atypicality of dermal lesions, failure in early diagnosis, and high bacillus load which can be a barrier in the eradication of the disease and act as a potential source of infection in areas where the disease has been eradicated. Our case showed up with plentiful dermal papules and nodules from two years ago which caused no discomfort. He had a history of leprosy 25 years ago and had been treated only with dapsone for 3 years. Therefore, the diagnosis of histoid type lepromatous leprosy was made and confirmed based on clinical and histopathological findings.

Epidemiological indices of non-melanoma skin cancers in Kermanshah, Iran

To obtain more accurate epidemiological data of non-melanoma skin cancers [NMSC]. This descriptive and analytical study was conducted amongst 133 patients pathologically documented as NMSC at Hajdaie Dermatological Clinic in Kermanshah, Iran, during 2009-10. In addition, specific findings such as type, location and number of the lesions, associated and underlying disorders were recorded. Statistical analysis was performed using SPSS version 16. Chi-square was used to compare the qualitative data. P-value <0.05 was considered statistically significant. A total of 133 patients with 235 lesions, and their age ranging between 25 and 97 years were enrolled in this study. The ratio of basal cell carcinoma [BCC] to squamous cell carcinoma [SCC] was 7.3/1. NMSC are mostly seen as facial solitary lesions in outdoor workers and the people with moderate brown skin. However, no difference was found in its prevalence between males and females or residents of urban and rural areas. Familial and personal history and host susceptibility played no important role in our patients either [P value >0.05]. Solar keratosis was the most common associated skin lesion. NMSC was seen slightly more common in males. BCC was considerably more common than SCC in this study. All obtained indices were practically consistent with previous reports. Besides, ultraviolet light was still the most important factor for NMSC induction in our area

Nasal deformity accompanying upper lip sebaceous carcinoma without neoplasm extension

Sebaceous carcinoma is very rare, occurring in less than 1% of cutaneous neoplasm. It may have numerous clinical presentations but typically appears as yellow or orange firm nodule in periorbital region. In the absence of usual clinical manifestations, diagnosis is difficult which calls for more studies to help with definitive diagnosis. We report an 81-year-old man whose sebaceous carcinoma was diagnosed by histopathologic and immunohistochemical studies. Our patient had clinical presentation as erythematous tumoral lesion, the unusual location of the lesion on the upper lip, very close to the nose, and nasal deformation similar to rosacea without any extension of tumour cells into nasal area. The mechanism by which sebaceous carcinoma resulted in nasal deformation is not clear

[Diffuse eruptive syringoma: a case report]

Eruptive syringoma is a rare benign tumor of eccrine sweat gland. Clinically, it presents as successive crops of symmetric, small yellow-brown to erythematous or skin-colored papules on the anterior body surfaces. It usually occurs in young women. Definitive diagnosis can be made on histopathological findings. The pathogenesis of eruptive syringoma is unclear but there are few reports about its association wit hantiepileptic drugs, radiation, trisomy 21, depilation and hyperthyroidism. The presented case was a 25-year-old woman who had referred with papules in forehead, periorbital regions, cheek, chin, chest, abdomen and forearm. Eruptive syringoma was confirmed based on its distinctive pathological findings. She thought her skin lesions were related to consumption of oral contraceptives. The importance of this disease is its cosmetic problem