RESUMO
BACKGROUND: Even pedicle screw fixation system is commonly used in spinal surgery, elderly patients with high bone fragility lack of bone elasticity, insufficient holding power of pedicle screw. Thus, there is a risk of loosening and pulling out the screws, leading to failure of spine reduction and fixation. Thus, we need to explore new method to increase the stability of the pedicle screw system. OBJECTIVE: To explore the long-term effect of pedicle screw internal fixation with bone cement in the treatment of different types of lumbar degenerative diseases with osteoporosis. METHODS: Sixty patients suffering from degenerative spinal disease with the complication of osteoporosis were randomly assigned to control group and trial group (n=30 per group). Before adopting the treatment of bone cement pedicle screw fixation and fusion, all patients had taken pre-operation examination, X-ray, CT and MRI scan. The patients in the control group were treated with conventional pedicle screw technology, and those in the experimental group were treated with bone cement on the basis of the conventional pedicle screw technology. Visual analogue scale score and Oswestry disability index were compared between the two groups 1 day before surgery, 1 week, 6 months, and 1 year after surgery. Complications were observed after surgery to evaluate the effect of the operation. RESULTS AND CONCLUSION: (1) At 1 week, 6 months and 1 year after surgery, the visual analogue scale score and Oswestry disability index were significantly better than those of pre-operation (P < 0.05). Visual analogue scale score and Oswestry disability index were significantly lower at 6 months and 1 year after surgery than those 1 week after surgery (P < 0.05). Visual analogue scale score and Oswestry disability index were significantly lower at 1 year than those at 6 months after surgery (P < 0.05). (2) Visual analogue scale score and Oswestry disability index were better in the trial group than those in the control group at 6 months and 1 year after surgery (P < 0.05). (3) The incidence of internal fixation rod loosening was lower in the trial group than that in the control group. (4) It is concluded that bone cement pedicle screw fixation and fusion in the treatment of degenerative spinal disease with osteoporosis can effectively improve the clinical symptoms and reduce the occurrence of complications. It is safe and effective in clinical application, and the long-term treatment effect is acceptable.