Acupoint selection pattern of chronic atrophic gastritis based on data mining methods of latent structure model and frequency item set / 中国针灸

<p><b>OBJECTIVE</b>To explore the acupoint selection pattern of chronic atrophic gastritis and provide reference for clinical treatment of chronic atrophic gastritis.</p><p><b>METHODS</b>The literature regarding acupuncture for chronic atrophic gastritis published before September 5th of 2016 was searched in the databases of CNKI, CBM, PubMed, etc. The information of symptoms and acupoint selection was extracted to establish medical database of chronic atrophic gastritis. The data mining methods of latent structure model and frequency item set were applied to analyze the acupoint selection pattern of chronic atrophic gastritis.</p><p><b>RESULTS</b>A total of 42 papers were collected in preliminary screening, and 32 papers were included, involving 604 medical cases. The data mining indicated 215 symptoms were involved in medical cases, including 16 high-frequency symptoms (stomach pain, stomach distension and hiccup, etc.), and the latent structure model of chronic atrophic gastritis symptoms was established. Fifty-two acupoints were identified, and high-frequency acupoints included Zusanli (ST 36), Zhongwan (CV 12), Neiguan (PC 6) and Weishu (BL 21), etc. Five frequency item sets of symptom-acupoint were identified, including stomach pain+stomach distension+Zusanli (ST 36)+Zhongwan (CV 12), etc. Six frequency item sets of symptom-syndrome-acupoint were identified, including stomach distension+dry mouth+dry defecation+insufficiency of stomach +Sanyinjiao (SP 6).</p><p><b>CONCLUSION</b>Acupuncture for chronic atrophic gastritis selected Zusanli (ST 36), Zhongwan (CV 12) and Neiguan (PC 6) as main acupoints, and selected other acupoints based on clinical symptoms. This could provide reference for clinical treatment of chronic atrophic gastritis.</p>

Acupoints selection rules analysis of ancient acupuncture for urinary incontinence based on data mining technology / 中国针灸

Based on ancient literature of acupuncture in Canon of Chinese Medicine (4th edition), the articles regarding acupuncture for urinary incontinence were retrieved and collected to establish a database. By Weka data mining software, the multi-level association rules analysis method was applied to analyze the acupoints selection characteristics and rules of ancient acupuncture for treatment of urinary incontinence. Totally 356 articles of acupuncture for urinary incontinence were collected, involving 41 acupoints with a total frequency of 364. As a result, (1) the acupoints in the yin-meridian of hand and foot were highly valued, as the frequency of acupoints in yin-meridians was 2.6 times than that in yang-meridians, and the frequency of acupoints selected was the most in the liver meridian of foot-jueyin; (2) the acupoints in bladder meridian of foot-taiyang were also highly valued, and among three yang-meridians of foot, the frequency of acupoints in the bladder meridian of foot-taiyang was 54, accounting for 65.85% (54/82); (3) more acupoints selected were located in the lower limbs and abdomen; (4) specific acupoints in above meridians were mostly selected, presenting 73.2% (30/41) to the ratio of number and 79.4% (289/364) to the frequency, respectively; (5) Zhongji (CV 3), the front-mu point of bladder meridian, was seldom selected in the ancient acupuncture literature, which was different from modern literature reports. The results show that urinary incontinence belongs to external genitalia diseases, which should be treated from yin, indicating more yin-meridians be used and special acupoints be focused on. It is essential to focus inheritance and innovation in TCM clinical treatment, and applying data mining technology to ancient literature of acupuncture could provide classic theory basis for TCM clinical treatment.

Exploration on the Famous Old TCM Doctor Wang Xingkuan’s Rules of Syndrome and Treatment of Chest Blocking and Heartache Based on Data Mining / 中国中医药信息杂志

Objective To explore Wang Xingkuan’s rules of syndrome and treatment of chest blocking and heartache (Xiongbixintong).Methods Collection of professor Wang Xingkuan’s 267 consilia of patients with Xiongbixintong for outpatients. Chinese medicine terminology was regulated and Excelldatabase was established. Symptom, syndrome element, pathogenesis and treatment were statistically described by using Weka3.6 software, and Apriori algorithm was adopted for the main pathogenesis→treatment analysis of association rules.Results Symptoms include:chest pain, heart palpitations, shortness of breath, pale tongue (dark) red, etc. Syndrome elements include:in liver, and heart, and blood stasis, phlegm, qi stagnation, etc. The key pathogenesis is liver-heart imbalance, including stagnation of liver qi, heart and blood stasis, deficiency of heart qi-ying, disturbing heart-mind, etc. The principle of treatment is liver-heart Tongzhi, so the treatment is of“liver” with Shu gan-mu;treatment of“heart” contains freeing channels, eliminating phlegm and blood stasis, quiet the heart, replenishing qi-ying, etc. The main pathogenesis related credibility→treatment was higher than 0.50;with high reliability, the liver-heart imbalance→liver-heart Tongzhi was 0.71. Medication includes catharsis and tonic,“catharsis” to salvia, allium macrostemon, pseudo-ginseng, bupleurum, etc;“tonic” to white ginseng, ophiopogon japonicus, radix paeoniae alba, poria with hostwood, polygala tenuifolia, etc. Conclusion “Xintongzhigan, liver-heart Tongzhi, catharsis and tonic” is Wang Xingkuan’s thoughts and experience in treating Xiongbixintong.