Relationship between the quality of life and occupational stress among workers in a chemical industry base / 中国职业医学

OBJECTIVE: To analyze the relationship between the quality of life and occupational stress among workers in a chemical industry base. METHODS: By a judgmental sampling method,the quality of life and occupational stress of 517 workers in a chemical plant were evaluated using the World Health Organization Quality of Life-BREF and the Occupational Stress Inventory-Revised. RESULTS: The median( P0-P100) of the scores of total quality of life was 51. 52(24. 62-74. 29)in the 517 chemical plant workers. The score of occupational role questionnaire( ORQ) of the workers was lower than that of the production laborer group [( 161. 40 ± 24. 99) vs( 183. 36 ± 22. 02),P < 0. 01]. The scores of personal strain questionnaire( PSQ) and personal resources questionnaire( PRQ) were higher than those of production laborer group[(100. 18 ± 20. 69) vs(97. 47 ± 13. 77),(131. 74 ± 17. 93) vs(128. 86 ± 18. 45),P < 0. 01]. The quality of life of the chemical plant workers who got higher scores in ORQ and PSQ were poorer than those who got lower scores in ORQ and PSQ( P < 0. 01). The quality of life of the chemical plant workers who got higher scores in PRQ were better than those who got lower scores in PRQ( P < 0. 01). The scores of total quality of life were negatively correlated with the scores of ORQ and PSQ( P < 0. 01),and positively correlated with the scores of PRQ( P < 0. 01). The key factors effected quality of life of chemical plant workers included personal strain,personal resources,occupational role,sleep time and injury on-the-job( P < 0. 05). CONCLUSION: The occupational stress of chemical plant workers may influence their quality of life. Reducing the occupational role and personal stress and increasing personal resources of chemical plant workers could improve their quality of life.

Study on challenge dose of pigeon paramyxovirus type 1 (Chuansha strain) / 病毒学报

In order to determine the challenge dose of pigeon paramyxovirus type 1 (PPMV-1) inactivated vaccine (S-1 strain). The virus titer of PPMV-1 E5 allantoic fluid (Chuansha strain) was determined using SPF chicken embryos in this research. After inoculating 30-day-old and 120-day-old pigeons with low-HI antibody against PPMV-1 (HI antibody < or =2) with different doses of PPMV-1 (Chuansha strain), the clinical symptoms and histopathological lesions of the challenged pigeons were examined. The results showed that the minimal lethal dose (MLD) of PPMV-1 (Chuansha strain) was 102.5 ELD50, so we determined that 10(5.5) ELD50, which was 1000 times the MLD, could be taken as the challenge dose in the vaccine efficacy test for PPMV-1 inactivated vaccine (S-1 strain).

Diagnostic value of ultrasonographic examination for hepatic steatosis in obese children / 中国当代儿科杂志

<p><b>OBJECTIVE</b>To evaluate the sensitivity and specificity of hepatic ultrasonography (US) for the diagnosis of hepatic steatosis in obese children, using ¹H magnetic resonance spectroscopy (¹H MRS) as the reference standard.</p><p><b>METHODS</b>A total of 162 obese children with age of 10.5 ± 2.2 years and BMI of 28 ± 4 were enrolled in this study. They accepted hepatic US and (1)H MRS examinations. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of US were calculated for the overall presence of hepatic steatosis by comparison with ¹H MRS results.</p><p><b>RESULTS</b>Using quantitative criteria of liver fat content (LFC) >5% determined by (1)H MRS, 95 children(58.6%)were diagnosed as having hepatic steatosis. The sensitivity and specificity of US in diagnosing steatosis were 91.6% (87/95) and 50.7% (34/67) respectively, with PPV of 72.5% (87/120), and NPV of 81.0% (34/42). Considerable overlap in LFC measured by ¹H MRS was observed between different grades from US findings: absent (LFC interquartile range: 1.3%-3.9%), mild (2.4%-10.7%), moderate (7.1%-20.2%) and severe (7.6%-28.8%) steatosis.</p><p><b>CONCLUSIONS</b>The US can yield a high sensitivity and low specificity in the diagnosis of hepatic steatosis in obese children, suggesting it can be used as a screening tool for hepatic steatosis. To improve diagnostics, ¹H MRS is needed to determine LFC.</p>