Clinical significance of rapid increase of heart rate at onset of treadmill exercise test / 中南大学学报(医学版)

OBJECTIVE@#To analyze the correlation between rapid increase of heart rate at onset of electrocardiogram treadmill exercise test and coronary artery lesion.@*METHODS@#We selected 245 patients who underwent electrocardiogram treadmill exercise and coronary angiography. The patients were divided into a coronary heart disease (CHD) group and a non-CHD group according to the Results of coronary angiography. The patients of the CHD group were divided into a single-vessel disease group, a double-vessel disease group, and a triplet-vessel disease group. The increased heart rate during the first minute (DeltaHR 1minute) of treadmill exercise test and the extent of coronary artery lesion were analyzed.@*RESULTS@#DeltaHR 1minute in the CHD group was significantly higher than that in the non-CHD group(P<0.01). DeltaHR 1minute had an increasing trend with the severity of coronary artery lesion. DeltaHR 1minute was positively correlated to the depression of ST segment and the severity of coronary artery lesion(r=0.252,0.470, P<0.01).@*CONCLUSION@#Patients with CHD have an increased DeltaHR 1minute. DeltaHR 1minute can be one of the indexes to estimate the extent of myocardial ischemia and coronary artery lesion.

Diagnostic value of chronotropic incompetence in coronary heart disease / 中南大学学报(医学版)

OBJECTIVE@#To determine the diagnostic value of chronotropic incompetence (CI) in coronary heart disease (CHD).@*METHODS@#Two hundred thirty three patients who underwent the electrocardiogram treadmill exercise test (TET) and coronary angiography (CAG) were included in this study. CAG was used as the standard of diagnosing CHD. The sensitivity, specificity, and accuracy of CI were compared with the traditional index of TET.@*RESULTS@#There was no significant difference between the sensitivity, specificity and accuracy of CI (81.7%, 64.3%, and 71.2% respectively) and those of the traditional index (73.1%, 69.3%, and 70.8% respectively, P> 0.05), while the specificity (87.9%) and accuracy (79.4%) were significantly higher after combining CI and the traditional index than that of the traditional index alone (P 0.05).@*CONCLUSION@#CI was a usefull index in diagnosing CHD. CI combined with the traditional index of TET can significantly improve the specificity and accuracy of TET for CHD.