Clinical significance of five tumor markers in the diagnosis of gastric cancer / 中国基层医药

Objective To investigate the value of the combined test of five tumor markers for gastric cancer diagnosis.Methods The electrochemical luminescence analyzer was used to measure the serum concentrations of CEA,CA125,CA199,CA724 and AFP in 127 gastric patients and 186 controls,and calculated the sensitivity and specificity.Results The concentrations of CEA (52.9 ±25.5)ng/mL,CA125 (54.2 ±40.6)U /mL,CA199 (42.4 ± 28.8)U /mL,CA724 (9.3 ±6.6)U /mL and AFP (22.6 ±11.4)ng/mL in the gastric cancer group were significantly higher than those in the controls,and the differences were statistically significant (t =6.006,7.118,6.033,6.683, 5.362,all P <0.05 ).The sensitivity in gastric cancer diagnosis with the combined test of five tumor markers (88.2%)was higher than the test of CEA (63.8%),CA125 (59.1%),CA199 (41.7%),CA724 (37.0%)and AFP (46.5%)alone,and the differences were statistically significant (χ2 =20.733,27.754,60.209,71.046, 50.270,all P <0.05).Moreover,the specificity in gastric cancer diagnosis with the combined test of five tumor markers (90.3%)was higher than the test of CA125 (79.3%),while lower than the test of CA724 (97.3%),and the differences were statistically significant (χ2 =9.137,7.832,all P <0.05).Conclusion The combined test of five tumor markers (CEA,CA125,CA199,CA724 and AFP)could increase the rate of gastric cancer diagnosis.

Traditional Chinese medicine and physical therapy on lumbar intervertebral disc herniation:clinical analysis of 86 cases / 医学研究生学报

Objective:Currently the treatment model of lumbar intervertebral disc herniation(LIDH) has changed from single surgical treatment to multisubjective comprehensive treatment.The purpose of this study was to observe the curative effect of synergic therapy with traditional Chinese medicine and physical therapy on LIDH.Methods:86 cases of LIDH treated with drawing,massage,Chinese herbal medicine injection and TDP radiation.Results:All the patients were followed for 1-7 months(mean 3 months).Convalescence 56 cases(65.1 %),effective 28 cases(32.6 %),no effect 2 cases(2.3 %),the total effective rate was 97.7%.Conclusion:The synergic therapy with traditional Chinese medicine and physical therapy was easy,safe and effective for LIDH.