Study On The Critical Maintenance Period Of Millipore Filter Membrane In Rats

The purpose of this study is to evaluate the critical maintenance period of absorbable membrane for guided bone regeneration. Fortynine Sprague-Dawley rats weighing about 300g were divided into seven groups. An 8 mm circular full-thickness defect in calvarial bone was made and then cellular acetate porous filter (Millipore filter(R)) was placed on the calvarial bone defect. The filter was removed at 2, 3, 4, 5, 6, 8 and 11 weeks after placement. Rats were sacrificed at 12 weeks the placement of cellular acetate porous filter. The specimens were stained with Hematoxylin-Eosin and observed under light microscope. The amount of regenerated bone was measured from both margin of calvarial bone defect (unit : mm). The results were as follows. Bone regeneration of each experimental group was increased gradually and the bond defect was almost completely filled with new bone in 5-, 6-, 8-, and 11-week experimental group. Histologic findings showed mild inflammatory response and granulation tissue formation without apparent adverse effects on the healing process. In 11-week experimental group, the bone defect was completely filled with new bone containing abundant osteoid which was oriented to the dural side and contribute to bony thickening. We suggest that non-absorbable membrane and bioabsorbable membrane presumably should remain intact for longer than 5 weeks to be effective.

Guided Bone Regeneration Of Calvarial Bone Defects Using Bioabsorbable Membrane And Demineralized Freeze Dried Bone In Rats

The purpose of this study was to evaluate new bone formation and healing process in rat calvarial bone defects using BioMesh(R) membrane and DFDB. Forty eight rats divided equally into 4 groups of 1 control group and 3 experimental groups. Standardized transosseous circular calvarial defects (8 mm in diameter) were made midparietally. In the control group, the defect was only covered with the soft tissue flap. In the experimental group 1, it was filled with DFDB only, in the experimental group 2, it was covered BioMesh(R) membrane only, and in the experimental group 3, it was filled DFDB and covered with membrane. At the postoperative 1, 2, 4, 8 weeks, rats were sacrificed and histologic and histomorphometric analysis were performed. These results were as follows. In histomorphometric analysis, It showed the greatest amount of new bone formation through experimental in the experimental group 3 (P < 0.001). The amount of new bone formation at the central portion of the defect was greater in the experimental group 3 than experimental group 2. BioMesh(R) membrane began to resorb at 1 week and resorbed almost completely at 8 weeks after operation. The collapse of membrane into the defect was observed through the experimental periods in the experimental group 2. In the area of collapsed membrane, new bone formation was restricted. These results suggest that maintenance of some space for new bone to grow is required in the use of BioMesh(R) membrane alone in the defect. It is also thought that use of the membrane may promote new bone growth in DFDB graft.

THE STUDY FOR HEMODYNAMIC CHANGE ON CORONAL APPROACH TO ZYGOMATICO-MAXILLARY COMPLEX FRACTURE

BACKGROUND: The coronal incision is versatile surgical approach to upper and middle region of the facial skeletal including the zygomatic arch. The advantages of coronal approach are minimal injury of facial tissue including facial nerve and satisfactory cosmetic result by hidden scar at hair. But wide exposure of scalp, its disadvantages are operation time and massive blood loss. METHODS: Thirty patients undergoing elective surgery were divided 3 groups. Group I used only coronal approach, group II used coronal with subciliary approach and group III used coronal with subciliary and intraoral approach. And then retrospected of the preoperative, postoperative red blood cell count, hemoglobin(Hb), hematocrit, transfused red blood cell units and platelet cell units, and the amount of infused crystalloids and colloids, and postoperative hemovac count was estimated. RESULTS: 1. Red blood cell count were decreased in all groups at immediated postoperation and decreased in all group of postoperative first day and decreased in group I, II but increased group III of postoperative third day. 2. Hemoglobin and hematocrit were decreased in all group at immediated postoperation and decreased in all group of postoperative first day and decreased in group I, II., but increased group III postoperative third day. 3. Platelet was decreased in all group at immediated postoperation, and decreased in group II, III but increased in group I of postoperative first day and decreased in group I but increased group II, III of postoperative third day. 4. Mean postoperative hemovac mean drainage group I of first day is 48.63+/-21.12ml and second day is 23.92+/-19.53ml and third day is 7.82+/-5.32ml and group II of first day 60.45+/-22.65ml and second day is 22.14+/-13.21ml and third day is 7.32+/-6.25ml. III group of first day 58.16+/-10.13ml and second day is 21.27+/-11.72ml and third day is 7.13+/-4.90ml. 5. Infusion of group I is mean PRC 1.08+/-0.91 pint, FFP 1.03+/-0.75 pint, crystalloid 2562.23+/-1345.53ml and group II is mean PRC 1.05+/-0.89 pint, FFP 1.71+/-0.78, crystalloid 2650.47+/-1096.36ml and group III is mean PRC 1.79+/-1.45 pint, crystalloid 3295.43+/-1472.432ml.

Reimplantation of Freeze-treated Autogenous Bone after Mandibulectomy: Report of Three Cases

Histopathologic changes of the craniomandibular joint after experimentally induced anterior disc displacement in rabbits

Conscious sedative drugs: A Clinical Study

An experimental study on the healing process of toothash, plaster of paris and autogenous bone composite grafting in dogs

Osteomyelitis Occurring Leukemia Patient: A Case Report

Leukemia is a malignancy caused by precursor cells of white blood cell. It is a malignant tumor of hematopoietic organs, characterized by the disorder of hematopoietic function due to the proliferation of immature bone marrow cells or lymphatic cells and by abnormal tissue infiltration of leukemic cells. The major signs of leukemia are caused by the failure of bone marrow function. As the number of red blood cells decreases, anemia is to appear. The number of white blood cells in leukemia is usually increased but immature white blood cells circulating the body has little defense ability, thus become susceptible to infection. 27 year-old female patient who was treated chemotherapy and bone marrow transplantation after diagnosed as chronic myelogenous leukemia(CML) was diagnosed as osteomyelitis in mandible after clinical and dental radiographic film examination. Because of the result of examination, the involved tooth of the patient was extracted accompanied by sequestrectomy and saucerization under general anesthesia. After the patient had long term medication of antibiotics, the lesion was healed. Therefore. author, et al. report this case with literature review.

Clinical study of chronic osteomyelitis

Chronic osteomyelitis is often considered difficult to treat and may lead to refratory condition in oral and maxillofacial region. Clinical features of chronic osteomyelitis includes pain, swelling, pus discharge, and radiographic change. There are many kinds of treatment of chronic osteomyelitis. One of the most important factors in treating osteomyelitis are removal of infectious foci and administration of massive antibiotics. Recently we reviewed 29 patients with chronic osteomyelitis who visited in our department and treated successfully with our treatment protocols, consisting of surgical intervention and intravenous antibiotics for 2 weeks, and followed by oral antibiotics for 6 weeks. It is concluded that combination of surgical intervention and antibiotic therapy are sufficient to treat the chronic osteomyelitis in oral and maxillofacial region.

The efficacy of antibiotic administration in the impacted mandibular third molar extraction

An effect of hyaluronic acid on the temporomandibular joint arthrocentesis

The soft tissue changes of the nasolabial region after maxillary le fort i advancement osteotomy

Surgical correction of masseter muscle hypertrophy: report of three cases

THE USE OF MEDPOR(TM) (POROUS HIGH-DENSITY POLYETHYLENE) IN ORAL AND MAXILLOFACIAL REGION

A EAGLE'S SYNDROME: A CASE REPORT

Eagle's syndrome is a condition that causes a dull, atypical neuralgic pain in the oropharyx, head and neck, often referred to the ear and the mastoid region in association with elongation of the styloid process of the temporal bone. Most people with abnormal styloid process have no symptoms. Recently, we have experienced a case of eagle's syndrome in a 38 year old woman. She had been suffered from sore throat, mild headache, and pharyngeal discomfort when swallowing and turning the head to the right side. It was successfully treated with surgical shortening of the styloid process via transpharyngeal approach under the general anesthesia, and then her symtom was relieved without complication.

A Clinicostatistical Study Of Non-Odontogenic Cysts: The Experience Over 10 Years

A cyst is cavity occuring in either hard or soft tissue with a liquid, semiliquid material, or air content. It is surrounded by a definite connective tissue wall or capsule and usually has an epithelial lining. The contained substance is a predominant feature in proportion to the size of the entire mass of tissue. It was classified as odontogenic cyst and non-odontogenic cyst in origin. The anatomic distribution, clinical features, final diagnosis, and treatment methods are discussed.

An experimental study on the bone regeneration of tibial bone defect

Fibrous dysplasia on left maxillofacial region

Aneurysamal bone cyst: report of a case

AN EXPERIMENTAL STUDY ON TISSUE RESPONSE FOLLOWING THE IMPLANTATION OF MEDPOR(R) (POROUS POLYETHYLENE) IN THE RATS