RESUMO
Pneumonia, along with graft-versus-host disease, is a major cause of morbidity and mortality in patients receiving bone marrow transplantation. The community respiratory virus infections have been found to be large causes of pneumonia. Upper respiratory infection with Parainfluenza virus can progress to severe lower respiratory diseases in bone marrow transplant recipients, of which clinical findings are similar to those of pneumonia by exotic opportunistic pathogens. We report a patient with chronic myelogenous leukemia who had suffered a community-acquired pneumonia by Parainfluenza virus type 3 after bone marrow transplantation.
Assuntos
Humanos , Transplante de Medula Óssea , Medula Óssea , Doença Enxerto-Hospedeiro , Leucemia , Leucemia Mielogênica Crônica BCR-ABL Positiva , Mortalidade , Vírus da Parainfluenza 3 Humana , Infecções por Paramyxoviridae , Pneumonia , TransplanteRESUMO
Pneumonia is a fatal disease in immunocompromised patients including bone marrow transplantation recipients. Etiological agents include fungi, cytomegalovirus, Pneumocystis carinii, influenza virus and parainfluenza virus. We describe a community-acquired respiratory syncytial virus pneumonia in a patient who received intense chemotherapy followed by peripheral stem cell transplantation for acute leukemia. The patient was treated with intravenous immunoglobulin and ribavirin aerosol. About 1 month later, she was recovered.