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Korean Journal of Nephrology ; : 321-325, 2003.
Artigo em Coreano | WPRIM | ID: wpr-48810

RESUMO

A 21-year-old male was presented with sudden headache, fever, petechiae and neck stiffness. The diagnosis of meningococcal meningitis was confirmed by examination of cerebrospinal fluid. The clinical symptoms of the illness were improved after treatment of antibiotics. However the patient developed generalized edema, oliguria, azotemia, and heavy proteinuria in the recovery phase of illness. Low serum C3 level was also noted. A kidney biopsy was performed and showed the features of postinfectious glomerulonephritis and typical subepithelial humps on electron-microscopic examination. His symptoms and laboratory findings were improved, and C3 level returned to normal range after conservative treatment. We suggest that a complement deficiency should be ruled out in patients of glomerulonephritis developed during the recovery phase of meningococcal meningitis. C3 nephritic factor detection and renal biopsy should be carefully considered in these patients.


Assuntos
Humanos , Masculino , Adulto Jovem , Antibacterianos , Azotemia , Biópsia , Líquido Cefalorraquidiano , Fator Nefrítico do Complemento 3 , Proteínas do Sistema Complemento , Diagnóstico , Edema , Febre , Glomerulonefrite , Cefaleia , Rim , Meningite , Meningite Meningocócica , Pescoço , Neisseria meningitidis , Oligúria , Proteinúria , Púrpura , Valores de Referência
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