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Obstetrics & Gynecology Science ; : 477-480, 2017.
Artigo em Inglês | WPRIM | ID: wpr-192005

RESUMO

The major risk factor for ovarian cancer (OC) is mutation of the BRCA1 or BRCA2 DNA mismatch repair genes, which occurs in approximately 10% of OC cases. Most previous studies have demonstrated that BRCA1- and BRCA2-mutated OCs are associated with better prognosis than sporadic OCs. However, information about the patterns and clinical course of the metastatic spread of BRCA-mutated OCs is limited. Herein, we describe a case of OC with a BRCA1 mutation and skin metastases in a 49-year-old patient, which to the best of our knowledge has not been reported previously.


Assuntos
Humanos , Pessoa de Meia-Idade , Reparo de Erro de Pareamento de DNA , Metástase Neoplásica , Neoplasias Ovarianas , Prognóstico , Fatores de Risco , Pele
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