Laparoscopic ovarian electrocautery versus human menopausal gonadotrophin in the management of infertility due to polycytic ovarian disease

Either of electrosurgical laparoscopic ovarian drilling [LOD]or gonadotropin [hMG] therapy is the second choice for induction of ovulation in clomiphene citrate resistance patients with polycystic ovarian disease, this study aim to compare both modalities [LOD and hMG]. Comparative study Bab El-Sharia University Hospital. Seventy five patients with anovulatory infertility due to PCOD were recruited from infertility clinic, the patients subdivided into two groups : first group [40 patients] treated with hMG, and second group [35 patients] subjected to LOD. The results of menstrual pattern, hormonal response, ovulation pattern and occurrence of pregnancy were compared between both modalities of treatment. Improved menstrual pattern 90% versus 70%, ovulation rate 79% versus 75%, pregnancy rate 40% versus 32.5% in LOD and hMG treated groups respectively. The rate of twin pregnancy was 7% in LOD treated group versus 23% in hMG treated group. No abortion occurred with LOD compared with 23% abortion rate in hMG treated group. The outcome of pregnancies in LOD was 100% healthy live birth compared with 76.9% in hMG treated group. NO hyperstimulation associated with LOD. The results with LOD are some what superior to the results with hMG

Relation between anovulatory infertility and temporal lobe epilepsy

This study was conducted on 100 women in the reproductive age. They were classified into three groups. Group I included 40 women with anovulatory infertility aged 28.4 +/- 7.7 years. They had no neuropsychiatric disorders. Group II included 40 women with temporal lobe epilepsy [TLE] aged 26.4 +/- 7.2 years. Group III [control] included 20 fertile women aged 26.2 +/- 5.5 years. They had neither gynecological nor neuropsychiatric disorders. All women were subjected to history, clinical and neurological examination, EEG, pelvic ultrasonography and estimation of serum FSH, LH, and progesterone in the midluteal phase. The study revealed that, there were some menstrual cycle disturbances associating temporal lobe epilepsy. There was no relation between disturbances and the duration of epilepsy, frequency of seizures, different antiepileptics and side of epileptic EEG focus. There was no evidence of TLE in cases of anovulatory infertility