RESUMO
The present study was conducted in order to evaluate the use of "platelet gel" - the autologous source of growth factors - in management of osseous defects in patients with adult periodontitis. Twenty periodontal osseous defects in ten patients suffering from moderate to advanced adult periodontitis were treated in this study [split mouth design]. One defect from each patient was treated surgically with placement of platelet gel, while the other was treated by mucoperiosteal flap without placement of gel. All patients were subjected to thorough clinical examination in selected sites, including; plaque index, papillary bleeding index, probing pocket depth and probing attachment level. All these clinical parameters were taken prior to surgery and at 3, 6 and 9 months post-surgically. These patients were also subjected to radiographic and densitometric evaluations before and at 3, 6 and 9 months after surgery, in order to record the changes in bone height of selected osseous defects using the "Schei method" and also to evaluate the changes in bone density in these defects using a densitometer. The results of the present study showed the following: Platelet gel, used in this study as an autologous source of growth factors, was well tolerated by human periodontal tissues. Both treatment modalities showed significant reduction in plaque index, papillary bleeding index probing pocket depth and probing attachment level between pre- and post-surgical follow up periods. Throughout the follow up period, no significant difference was found with respect to plaque index on comparing test and control sites, while significant difference was detected at 3, 6 and 9 months post-surgically with respect to papillary bleeding index and probing attachment level, and at 6 and 9 months for probing pocket depth in the favor of the test sites. Radiographic analysis revealed improvement in bone height between pre- and post-surgical follow up periods in both test and control sites, but this improvement was not significant. On comparing test and control sites, it was found that test sites showed greater increase in bone height, particularly at 6 and 9 months post-surgically. However, also this increase was not significant. An improvement in mineral content was detected in both test and control sites throughout the observation periods. A statistically significant difference was detected between test and control sites at 3, 6 and 9 months post-surgically with the test sites exhibiting greater improvement
RESUMO
The present study was undertaken to determine the role of lupus band test as a prognostic and diagnostic value in 17 patients with LE using direct fluourescent an-tibody technique. They were 9 CDLE patients and 8 SLE patients and other 10 normal indivudals as controls. From the results, the following can be concluded:1 - The high frequency of lupus band test in SLE in comparison to CDLE. 2 - Positive lupus band test in patients with CDLE may represents a prognostic value since some of these patients develop systemic manifestions later in the course of the disease. 3 - Positive lupus band test in SLE patients with appraently normal oral mucosa may help to confirms a diagnosis of SLE in patients where a skin biopsy is not possible