[Non Hodgkin's lymphoma and chronic hepatitis C virus infection: a non- fortuitous association .Two cases report]

Many authors suggest the role of hepatitis C virus [HCV] infection in the pathology of B-cell non Hodgkin's lymphomas; this is based on epidemiological, physiopathological and therapeutic arguments. The frequency of the association with hepatitis C virus infection is variable in the different study [1 to30%]. We report two cases of hepatitis C virus infection in association with non Hodgkin's lymphomas. The first case presented a low grade splenic and nodal non-Hodgkin's lymphoma associated with hepatitis C virus infection and complicated by hepato-cellular carcinoma. The second case presented a high grade nodal non-Hodgkin's lymphoma associated with HCV infection. Our cases report confirms the hypothesis of a key role of hepatitis C virus in the pathogenesis of B-cell lymphoproliferative disorders and in particular the non-Hodgkin's lymphoma. Although of several hypothesis concerning the ethiopathogenic mechanisms of this association, new studies will necessary to improve the real mechanism of this association

[Prune belly syndrome: Early prenatal diagnosis and management]

Prune Belly syndrome in characterized by a combination of megacystis, anterior abdominal wall distension with deficiency of the abdominal wall musculature, and bilateral cryptorchidism. Diagnosis is easy after 15 weeks of gestation, but may be difficult at the end of the first term. Authors report 2 cases of Prune Belly syndrome diagnosis at 11 and 14 weeks of gestation respectively. Afterliterature review, diagnosis and prognosos particularities of this syndrome are discussed