Clinico-pathological observations and ultra-structural alterations of nasal mucosa after cessation of airflow light and electron microscopic study of laryngectomy patients

The effect of the airflow cessation on the human nasal mucosa can be studied conveniently in the laryngectomy patients. Twenty-one of laryngectomized patients and 10 apparently healthy adults served as controls were rhinoscopically examined. By time, the nasal mucosa became thinner and its color changed. Mucociliary clearance showed many variations following surgery when compared with control group. Light and transmission electron microscopic examination of nasal mucosal specimens showed significant changes in the respiratory lining of the nose. The results of this study concluded that the airflow changes have effects on nasal mucous structural and function