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JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2011; 21 (9): 539-541
em Inglês | IMEMR | ID: emr-136651

RESUMO

To determine the outcome of tetanus in neonates treated with intrathecal tetanus immunoglobulin in terms of mortality and hospital stay. Experimental study. Paediatric Unit I, Bahawal Victoria Hospital, Bahawalpur, from April 2004 to December 2007. Seventy neonates with diagnosis of neonatal tetanus were included in the study. The neonates with fits due to causes other than tetanus were excluded. Thirty five patients received intrathecal immunoglobulin in addition to standard treatment [group A] while, the other 35 patients received only standard treatment [group B]. The mortality and duration of hospital stay in 2 groups were recorded. In group A, mean duration of hospital stay was 10 days while, in group B it was 13 days [p<0.001]. One patient from group A and 8 patients from group B expired [p=0.026]. The occurrence of refractory fits, repeated apnoeic episodes and high grade fever did not show any statistically significant difference in the 2 groups. Intrathecal anti-tetanus immunoglobulin in addition to the standard improved the outcome of neonatal tetanus in terms of mortality and hospital stay

2.
Professional Medical Journal-Quarterly [The]. 2011; 18 (3): 445-449
em Inglês | IMEMR | ID: emr-113360

RESUMO

To know the status of hepatitis C virus [HCV] infection in children admitted in Pediatric ward of Bahawal Victoria Hospital Bahawalpur. Cross-sectional descriptive study. Pediatric unit-1 Bahawal Victoria Hospital Bahawalpur over a period of 2 months and 15 days. This study was conducted over 500 children admitted in children ward-1 of Bahawal Victoria Hospital Bahawalpur. Children of 1-15 years of age were included in the study. The blood samples of these children were taken at the time of admission and serum was tested for HCV with ICT method and later on confirmed by ELISA. Children having HCV infection were tested for SGPT level. Different risk factors for transmission of HCV infection were also studied. Out of 500 children 43 were HCV positive by ICT method. Out of these 43 ICT positive children 38 were confirmed by ELISA. In this way 7.6% children were found positive for HCV. In 23 cases [60.5%] SGPT was raised [>40]. Statistically significant risk factors for transmission of HCV infection found in this study were past history of blood transfusion and history of injections in past. HCV infection is quite common in children. Safe blood transfusions and use of disposable and sterilized syringes is important for prevention of this infection

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