Giant Cell Tumour of Spine - A Rare Case

Spine is an unusual site for giant cell tumour (GCT). The largest of the series was published by Dahlin in the year 1977. Giant cell tumour of the spine is most aggressive benign tumour of the spine with unpredictable outcome. We report a case of 29 years old male patient with giant cell tumour of spine, clinically diagnosed as spinal tuberculosis. Patient presented with cord compression and neurological deficits in upper limb. Patient presented with clinical as well as radiological instability.Giant cell tumour (GCT) of bone is a rare neoplasm that accounts for approximately 5 % of all primary bone tumours in adults.1 GCT most frequently occurs at the end of long bones.2 Giant cell tumour also occurs in the mobile spine, but this location accounts for only 2 - 4 % of cases.3 In all locations, the neoplasm occurs most commonly between the ages of 20 - 45 years and it affects males and females with equal frequency.1 It is the most aggressive of the benign primary tumours of the spine,4 with a high predilection for recurrence. Due to the unusual site and nonspecific symptoms Giant cell tumour of spine is a challenge to the treating surgeons. We report a case of giant cell tumour cervical vertebrae where in patient presented with signs and symptoms of cord compression and was provisionally diagnosed as tuberculosis spine.

Pancreatic Neuroendocrine Tumour- An Interesting Case Report.

Neuroendocrine neoplasms of the pancreas are moderately uncommon, representing roughly 1–2% of every pancreatic neoplasm, and are composed of epithelial neoplastic cells with neuroendocrine differentiation. Neuroendocrine neoplasms are potentially malignant including well-differentiated types and poorly differentiated types. We present a case report of a 40-year-old female patient with complaints of pain abdomen after consumption of food and loss of weight and appetite over a period of three months with a diagnosis of pancreatic neuroendocrine tumour made based on histopathology.

Synovial Metaplasia- A Case Report of Synovial Chondromatosis in a Young Adult

Synovial chondromatosis is an uncommon benign condition emerging from the synovial membrane of the joints, synovial sheaths or bursae around the joints1. Synovial chondromatosis commonly influences the big joints in the third to fifth decade of life. The motivation behind this case report is to record this uncommon synovial pathology in 25 years young male which required open synovectomy and debridement to treat it. Synovial chondromatosis is an uncommon benign condition. Patients generally present with swelling, pain and including the synovial covering of joints, synovial sheaths and movement restriction2.

Primary Papillary Serous Carcinoma of Cervix: A Rare Variant of Cervical Malignancy

Papillary serous carcinoma of the uterine cervix is a very rare tumour, and is a recently described variant of cervical adenocarcinoma. It is an aggressive tumour with unpredictable course and poor prognosis. The incidence of cervical adenocarcinoma is 5–15%. This variant accounts for less than 50 cases in literature, has bimodal age distribution with one peak occurring less than 40 years and other occurring greater than 65 years age groups. Here, we present a 53 year-old woman presented with severe low backache and lump abdomen of 4 months duration. Per vaginal examination showed endophytic growth high up in the cervix. Pap smear and cervical biopsy done. Histopathological examination of cervical biopsy revealed papillary serous adenocarcinoma. Later, we received hysterectomy specimen with regional lymph nodes, which showed tumour limited to endocervix.