RESUMO
No abstract available.
Assuntos
Idoso , Humanos , Administração Metronômica , Capecitabina , Neoplasias Colorretais , Tratamento FarmacológicoRESUMO
Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare subtype of malignant non-Hodgkin lymphoma, in which 40% of the cases show spontaneous regression without aggressive treatment. Surgery and focal radiation therapy are the primary forms of treatment for this disease; however, if pcALCL is accompanied by multifocal skin lesions, chemotherapy is also common. The prognosis for pcALCL is generally excellent, with a 5-year survival rate of 85-100%. However, pcALCL with extensive limb disease typically has a poor prognosis. Here, we present a case of pcALCL with extensive limb disease that resulted in the patient's death, despite the use of aggressive chemotherapy.
Assuntos
Tratamento Farmacológico , Extremidades , Linfoma , Linfoma não Hodgkin , Linfoma Anaplásico Cutâneo Primário de Células Grandes , Prognóstico , Pele , Taxa de SobrevidaRESUMO
No abstract available.
Assuntos
Adulto , Humanos , Masculino , Adenocarcinoma/química , Antineoplásicos/uso terapêutico , Biópsia , Carcinoma de Células Grandes/química , Carcinoma Neuroendócrino/química , Carcinoma Pulmonar de Células não Pequenas/química , Resistencia a Medicamentos Antineoplásicos , Neoplasias Pulmonares/química , Imageamento por Ressonância Magnética , Inibidores de Proteínas Quinases/uso terapêutico , Quinazolinas/uso terapêutico , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Biomarcadores Tumorais/análiseRESUMO
BACKGROUND/AIMS: Percutaneous endoscopic gastrostomy (PEG) is a widely-performed procedure for patients undergoing enteral feeding. Due to frequent complications, careful management after the PEG is required. In this study, we investigated the risk factors associated with early exchange of PEG tube. MATERIALS AND METHODS: We did a retrospective survey of 72 patients who received a PEG between January 2009 and April 2014. All patients underwent a tube exchange or removal after the first PEG. Patients who had an exchange within 6 months were defined as 'early exchange' group and the others, as 'late exchange' group. We analyzed the relationship between early exchange and pre-PEG status. RESULTS: Mean age of patients was 67.5+/-18.3 years. The most frequent mental status and performance status before the first procedure, was 'alert' (n=48, 66.7%) and Eastern Cooperative Oncology Group (ECOG) score was 4 (n=28, 39.8%). Mean BMI was 20.2+/-3.7 kg/m2 and the majority of PEG cause was cerebrovascular accidents (n=23, 31.9%). Many patients had a tube exchange (or removal) because of tube dysfunction (n=32, 44.4%). The 'early exchange' group showed a lower BMI than 'late exchange' group (19.7+/-3.57 kg/m2 vs. 22.4+/-3.87 kg/m2, P value 0.009). 'Underweight' (BMI less than 18.5 kg/m2) group was more frequently observed in 'early exchange' group. There was no significant difference in pre-PEG status and post-PEG complication between the 2 groups. CONCLUSIONS: A lower BMI was associated with early exchange of PEG. Health providers should pay attention to the nutritional status of PEG patients.
Assuntos
Humanos , Índice de Massa Corporal , Endoscopia , Nutrição Enteral , Gastrostomia , Estado Nutricional , Estudos Retrospectivos , Fatores de Risco , Acidente Vascular CerebralRESUMO
Gastric schwannomas are rare benign tumors among the mesenchymal tumor of the gastrointestinal tract, arising from the nerve tissue which has a schwann cell sheath. These neoplasms are grossly similar to gastrointestinal stromal tumor (GIST), however, the clinical course of GIST is more aggressive compared to that of schwannomas. Synchronous occurrence of gastric epithelial and subepithelial tumors is rare. Besides, most subepithelial lesions are GIST. We present the case of a 57-year-old male with synchronous gastric schwannoma and gastric adenoma in the stomach. We found a gastric subepithelial lesion incidentally, the size of which was increasing and tubular adenoma was discovered in the covering mucosa during endoscopy follow-up. The synchronous lesion was removed by wedge resection, which was diagnosed as schwannoma with adenoma.