Autism Spectrum Disorder Categories and Social Responsiveness among Adults with Autism Spectrum Disorder.

Introduction: Autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication. Individuals with autism spectrum disorder usually have problems with social responsiveness which in turns effects their social communication and results in confined repetitive pattern of behaviour and interests. However the existing literature is limited in demonstrating the importance of social responsiveness and its impact on gender and ASD categories. Objective: The purpose of this study was to determine the impact of ASD categories on social responsiveness in adults with ASD and investigate social responsiveness among male and female adults with ASD. Methodology: The study utilized data from 60 adults diagnosed with autism spectrum disorder with categories mainly, mild, moderate and high functioning. Adults of both genders (male and female) participated in this study with Social Responsiveness (SR) as a variable over 7 months from October 2021 to February 2022, using the Social Responsiveness Scale-2 (SRS-2 Adult Relative/Other online form). Results and Conclusion: One-way ANOVA test showed significant difference (p<0.001, df=2) between ASD categories. Tukey's Post Hoc Analysis revealed significant (p<0.001) difference between ASD categories from each other. Gender had no significant impact on ASD, and the severity of ASD varies between groups. Thus, this study fills a large knowledge gap on the influence of gender, categories and social responsiveness on adults with ASD.

Emergence of methicilllin resistant Staphylococcus aureus (MRSA) associated with wound infections.

In a hospital setting antimicrobial resistant organisms especially Methicillin resistant Staphylococcus aureus (MRSA) has emerged as an important variable influencing patients' outcome and overall resource utilisation. The present study was undertaken to find out the proportion of MRSA and other organisms and their antimicrobial resistance pattern in admitted cases with postoperative wound infections. A total of 50 wound swabs were collected irrespective of age and sex of the patients from National Institute of Traumatology and Orthopaedics Rehabilitation (NITOR). The laboratory work was performed in the department of microbiology of National Institute of Cardiovascular Diseases (NICVD). Isolation, identification and susceptibility testing was done according to the guideline of the National Committee for Clinical Laboratory Standards (NCCLS, 1998). Out of the 50 samples 34 yielded growths of which 15 had growth of single organism and 19 had mixed growth of 2 to 3 organisms. Four different types of organisms were identified. Highest percentage was Escherichia coli 55.9%, followed by Pseudomonas sp. 52.9%, Proteus sp. 38.2%, and Staphylococcus aureus 17.6%. Of the 6 isolates of S aureus 5 (83.3%) were MRSA. Therefore it can be concluded that MRSA is existing in the hospital premises of NITOR, which can endanger the life of many. This study emphasises that susceptibility testing of all clinical isolates is essential to reduce the morbidity, mortality and longer duration of hospital stay. In addition proper management of the cases can decrease the spread of multiple drug resistant organisms in the community.

Zinc concentration of breast milk and its diurnal variation in Bangladeshi mothers.

Little is known about the zinc content of breast milk in developing countries. Zinc content in breast milk was analyzed in 34 mothers of low socio-economic status; 17 were primiparae and 17 multiparae. Women in their 6th to 36th week of lactation provided 3 samples of breast milk at different times within a single day. The mean zinc concentration in breast milk (micrograms/ml) was 1.89 +/- 0.64 with a range from 0.17 to 4.38 micrograms/ ml. Zinc content in the morning, midday and evening samples were 2.1 +/- 0.84, 1.74 +/- 0.53, 1.84 +/- 0.69 respectively. There was significant variation between morning and midday samples (p = 0.038). Maternal age, parity, nutritional status or age of the child did not affect the zinc content of milk in the population studied.

Experience with norethisterone enanthate as injectable contraceptive.

Norethisterone Enanthate (NE) was used in 151 women as injectable contraceptive. Pregnancy due to method failure was 2% whereas the overall pregnancy was 4%. The results have been discussed.