An infant with a palatal fistula secondary to Candida infection

Candida osteomyelitis affecting maxillofacial bones has been scantly documented in the literature. Infantile osteomyelitis is an uncommon and life-threatening disease. Candida osteomyelitis causes significant morbidity. The present report describes a case of a 9-month-old infant with infantile osteomyelitis secondary to Candida infection. This report describes its presentation and the management of palatal fistula in an infant.

Factor Structure Of Type D Scale In Malaysian Patients With Coronary Artery Disease

Objective: Type D personality, tendency trait to experience increased NA (Negative Affect) and SI (Social Inhibition) has been associated with negative psychological conditions linked to heart disease. This study aimed to examine the psychometric properties of the Malay version of Type D personality scale (DS14) among Malaysian patients with coronary artery disease (CAD). Methods: In this cross-sectional study 195 patients diagnosed with CAD were selected from National Heart Institute, Kuala Lumpur. They completed the questionnaire including demographic information and the Malay version of DS14 and Hospital Anxiety and Depression Scale (HADS). Results: The structural validity, as demonstrated by exploratory factor analysis of the DS14 was acceptable. The Cronbach's α coefficient for the NA and SI subscales were 0.876 and 0.732, respectively. With the standardized cut-off of NA ≥ 10 and SI ≥ 10, 28.2% of the patients with CAD were defined as having a Type D personality. Anxiety was significantly higher among patients with Type D personality. Conclusion: The results indicate that the Type D personality (DS14) questionnaire is a valid and reliable tool in the Malaysian population. The prevalence of Type D personality in Malaysia falls close to what has been found in Western countries, at least for CAD patients. This study indicates also that it is possible to use the DS14 among the Malaysian population in future cross-cultural studies.

Scrutinizing the aqueous extract of leaves of Pedalium murex for the antiulcer activity in rats

Peptic ulcer is manifested largely due to an alteration in lifestyle and diet. The antiulcer efficacy of the aqueous extract of leaves of Pedalium murex on ethanol induced gastric lesions was investigated in our studies. This has been substantiated by ascertaining the content of total acid, acid volume, total protein, ulcer index and glutathione. Ulceration was induced in 36 hours fasted rats by the administration of 80% ethanol [1ml/kg] orally. The reference standard [famotidine, 3mg/kg] and aqueous extract of leaves of Pedalium murex in doses of 50, 100, 200mg/kg was given to different groups, one hour before the administration of ethanol. Marked gastric mucosal lesions were observed with ethanol. A perceptible elevation in ulcer index, total acidity, acid volume, total protein and diminution of glutathione was observed. Pretreatment with aqueous extract of leaves of Pedalium murex particularly at a dose of 200mg/kg in a single schedule and 100mg/kg for 15 and 30 days treatment annihilated these alterations and elevated the level of glutathione. Therefore the aqueous extract of leaves of Pedalium murex could be regarded as a favorable antiulcerogen which could be attributed to its content of flavonoids and mucilage