Histopathological Spectrum of Cysticercosis and thir Demographic Study in Tertiary Care Hospital at N.M.C.H., Patna, Bihar

Introduction: Cysticercosis is a systemic manifestationcaused by dissemination of larval form of Tacnia solium, alsocalled as pork tape worm, is a major public health problem indeveloping countries. The aim of present study was undertakento evaluate the histopathological spectrum of cysticercosiswith their demographic pattern in our tertiary care hospital.Material and methods: A total of 3055 patients of differentage, sex and religions with nodular swelling in different partsof their body were attending in different OPD. From all thepatients, a total of 3055 specimens were received in ourdepartment for histopathological evaluation.Results: Out of 3055 specimen received for biopsy, 8 (0.26%)cases were diagnosed as cysticercosis. Out of which 50%cases (4 cases) were of less than 20 years of age group and62.5% cases were female patients. The disease was found inboth religions Hindus and Muslims (87.5% in Hindus)Conclusion: Even fine needle aspiration cytology (FNAC)has very limited value in diagnosis of cysticercercosis inmost of the cases and could not be recommended due topoor diagnostic value and in cases of neurocysticercosis aswell as ocular or orbital cysticercosis, FNAC could not beattempted due to risky procedure with very limited diagnosticvalue, although serological tests are done for the seriouscomplications of cysticercosis,but the final diagnosis isHistopathological study which is justified and the ultimatediagnostic technique for correct diagnosis.

Coagulase negative Staphylococci as causative agents of urinary tract infections-prevalence and resistance status in IGIMS, Patna.

Previously considered solely as the laboratory contaminants and normal flora of skin in man, coagulase negative Staphylococci are now a major cause of nosocomial and opportunistic infections. This study was conducted at IGIMS, Patna to find out the coagulase negative Staphylococcus isolates from urine and their antimicrobial resistance. In a period of ten months, the relative frequency of main coagulase negative Staphylococci were as follows--Staphylococcus epidermidis-45.90%, Staphylococcus saprophyticus 34% and Staphylococcus haemolyticus-8.50%. others were 11.60%. most of the Staphylococcus saprophyticus was isolated from young female patients suffering from uncomplicated acute cystitis and Staphylococcus epidermidis was mainly from patients with indwelling catheters and complicated cases. Staphylococcus saprophyticus showed the highest sensitivities to all the antimicrobials whereas Staphylococcus haemolyticus had the highest resistance rates. 66.6% of staphylococcus epidermidis and 60% of staphylococcus haemolyticus were resistant to oxacillin, whereas only 10% of staphylococcus saprophyticus resistant and 90% were sensitive to it. As is in the emerging state, vancomycin resistance was very less but in future it may cause a major problem to treat these cases. So this area needs further exploration.